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2-Azido-β-D-glucose tetraacetate

CAS 80321-89-7C14H19N3O9Chemical Synthesis

2-Azido-β-D-glucose tetraacetate (CAS: 80321-89-7) is a crucial chemical intermediate with the molecular formula C14H19N3O9 and a molecular weight of 373.32 g/mol. This acetylated azide derivative of glucose serves as a versatile building block in carbohydrate chemistry and organic synthesis. It is particularly valuable for introducing azido functionalities into complex molecules, enabling further derivatization through click chemistry and other bioconjugation strategies.

IUPAC
1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-β-D-glucopyranose,2-Azido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosyl acetate
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2-Azido-β-D-glucose tetraacetate (C14H19N3O9) — chemical structure, CAS 80321-89-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Aliphatic AzidesAzidesBuilding BlocksCarbohydrate AzidesCarbohydrate ChemistryCarbohydrate DerivativesChemical BiologyChemical SynthesisAlkynes and Other ReagentsNitrogen Compounds
01 /Applications

Carbohydrate Synthesis

This compound is a key intermediate in the synthesis of complex carbohydrates and glycoconjugates. Its azido group can be readily transformed into other functionalities or used in click chemistry reactions.

Chemical Biology

It serves as a valuable tool for probing biological systems, enabling the study of glycosylation pathways and the development of glycomimetics.

Organic Synthesis Building Block

As an acetylated azide of glucose, it provides a protected and activated form for incorporating a glucose moiety into various organic molecules.

Bioconjugation Chemistry

The azido group is ideal for copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions, facilitating the conjugation of biomolecules.

02 /Properties
Molecular weight373.32
Empirical formulaC14H19N3O9
Assay≥98% (HPLC)
Optical activity[α]/D +2.9±0.4°, c = 1 in chloroform
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
Warning

Hazard statements

  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H332Harmful if inhaled
  • H335May cause respiratory irritation
  • H341Suspected of causing genetic defects

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)20/21/22-36/37/38-68
Safety statements (S)26-36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
80321-89-7
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Azido-β-D-glucose tetraacetate used for?

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2-Azido-β-D-glucose tetraacetate is primarily used as a versatile building block in carbohydrate synthesis, chemical biology, and bioconjugation chemistry, particularly for introducing azido functionalities.

What is the CAS number and formula for 2-Azido-β-D-glucose tetraacetate?

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The CAS number is 80321-89-7 and the molecular formula is C14H19N3O9.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Azido-β-D-glucose tetraacetate with a purity of ≥98% (HPLC). This product is supplied for research and development purposes and is not intended for USP, BP, EP, or any other pharmacopoeia, nutraceutical, or food grade applications.

What are the safety considerations for handling 2-Azido-β-D-glucose tetraacetate?

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2-Azido-β-D-glucose tetraacetate is classified with GHS07 and GHS08 symbols, carrying a 'Warning' signal word. It has hazard statements including H302, H312, H315, H319, H332, H335, and H341, indicating it is harmful if swallowed, in contact with skin, or if inhaled, causes skin and serious eye irritation, and may cause genetic defects. Appropriate personal protective equipment, including a dust mask (N95 US type), eyeshields, face shields, and gloves, should be used.

How is 2-Azido-β-D-glucose tetraacetate typically packed and shipped?

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As a global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and shipping procedures are followed for 2-Azido-β-D-glucose tetraacetate, adhering to all relevant regulations for chemical transport.

How can I request a sample or quote for this chemical?

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To request a sample or a quote for 2-Azido-β-D-glucose tetraacetate, please contact our sales team through the website or by providing your details via the enquiry form.

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