Harmine
Harmine (CAS: 442-51-3), with the molecular formula C13H12N2O and a molecular weight of 212.25 g/mol, is a naturally occurring beta-carboline alkaloid. It is recognised for its applications in biochemical research, particularly in fluorescence resonance energy transfer (FRET) studies. Harmine serves as a valuable building block in chemical synthesis and is of interest in cell biology research.
- IUPAC
- 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole
Fluorescence Resonance Energy Transfer (FRET) Studies
Harmine has been employed as a donor molecule in fluorescence resonance energy transfer (FRET) investigations. For instance, it was used in conjunction with silver nanoparticles (AgNPs) to explore energy transfer dynamics in a specific study.
Biochemical Research
As a bioactive small molecule, Harmine finds application in various biochemical research settings. Its properties make it a subject of interest for understanding biological processes at a molecular level.
Chemical Synthesis
Harmine functions as a useful building block in organic synthesis. Its heterocyclic structure offers potential for the development of novel chemical entities and complex molecular architectures.
Cell Biology Investigations
The compound is relevant in cell biology research due to its bioactive nature. It can be used to study cellular mechanisms and pathways where its specific molecular interactions are of interest.
| Molecular weight | 212.25 |
|---|---|
| Empirical formula | C13H12N2O |
| Assay | 98% |
| Application | Harmine was used as a donor in the fluorescence resonance energy transfer (FRET) study between harmine and silver nanoparticles (AgNPs)1. |
| Melting point | 262-264 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H319Causes serious eye irritation
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CDC2(983), CYP2D6(1565) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Harmine used for?
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Harmine is utilised in biochemical research, particularly in fluorescence resonance energy transfer (FRET) studies and as a building block in chemical synthesis and cell biology investigations.
What are the CAS number and formula for Harmine?
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The CAS number for Harmine is 442-51-3, and its molecular formula is C13H12N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Harmine with a purity of 98% (Assay). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety considerations when handling Harmine?
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Harmine is classified under GHS07 with a Warning signal word. It carries hazard statements H302, H312, H319, and H332, indicating it is harmful if swallowed, in contact with skin, and if inhaled, and causes serious eye irritation. Appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves, should be worn.
Does Tech Serve Solutions export Harmine?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Harmine.
How can I request a sample or quote for Harmine?
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Please contact our sales team directly via the website to request a sample or a quotation for Harmine.
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