Guvacine hydrochloride
Guvacine hydrochloride (CAS 6027-91-4), a bioactive small molecule with the formula C6H9NO2 · HCl and a molecular weight of 163.60, is a valuable research chemical. Primarily known for its role in neuroscience and cell biology, it acts as a GABAergic compound. Guvacine hydrochloride is utilized in scientific research settings for its effects on ion channels and neurotransmission, particularly within studies investigating GABA and glycine receptor modulation. It is supplied as a white solid.

Neuroscience Research
Guvacine hydrochloride serves as a research tool in neuroscience for studying neurotransmission and the function of GABA and glycine receptors. Its interaction with ligand-gated ion channels makes it relevant for investigating cellular signaling pathways.
Cell Biology Studies
Within cell biology, guvacine hydrochloride can be employed to explore cellular responses and signaling mechanisms. It is a useful compound for researchers investigating the effects of specific molecular modulators on cell function.
Pharmacological Investigations
As a GABAergic agent, guvacine hydrochloride is used in pharmacological research to understand the mechanisms of action related to GABA receptors. This aids in the development of research models for neurological processes.
| Molecular weight | 163.60 |
|---|---|
| Empirical formula | C6H9NO2 · HCl |
| Assay | ≥97% (NMR) |
| Form | solid |
| Colour | white |
| Solubility | H2O: solubleethanol: slightly soluble |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Guvacine hydrochloride used for?
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Guvacine hydrochloride is used in scientific research, particularly in neuroscience and cell biology, for studying neurotransmission and its effects on GABA and glycine receptors and ion channels.
What is the CAS number and formula for Guvacine hydrochloride?
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The CAS number for Guvacine hydrochloride is 6027-91-4 and its empirical formula (Hill notation) is C6H9NO2 · HCl.
What grade and purity does Tech Serve Solutions supply for Guvacine hydrochloride?
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Tech Serve Solutions supplies Guvacine hydrochloride with a purity of ≥97% (NMR). TSS does not represent this product as USP, BP, or EP grade.
How should Guvacine hydrochloride be handled safely?
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Guvacine hydrochloride is a Warning substance (GHS07) that can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use a dust mask type N95 (US), together with eyeshields and gloves. Avoid breathing dust. If in eyes, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do. Continue rinsing.
Is Guvacine hydrochloride a controlled substance?
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The provided data does not indicate that Guvacine hydrochloride is a controlled substance.
How is Guvacine hydrochloride packed and shipped?
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Guvacine hydrochloride is typically supplied as a white solid. Specific packing and shipping details for export can be discussed upon inquiry.
How can I request a quote or sample of Guvacine hydrochloride?
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To request a quote or sample of Guvacine hydrochloride, please contact Tech Serve Solutions directly through our website or designated sales channels.
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