Guanosine 5′-triphosphate sodium salt hydrate

CAS 36051-31-7C10H16N5O14P3 · xNa+Biochemicals & Reagents

Guanosine 5′-triphosphate sodium salt hydrate (CAS 36051-31-7), with the empirical formula C10H16N5O14P3 · xNa+ and a molecular weight of 523.18 (free acid basis), is a crucial biomolecule. It serves as a vital cofactor and substrate in numerous cellular processes, including energy transduction, signal transduction, and nucleic acid synthesis. Supplied by Tech Serve Solutions as a white powder, it is essential for biochemical research.

IUPAC: GTP

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Guanosine 5′-triphosphate sodium salt hydrate (C10H16N5O14P3 · xNa+) — chemical structure, CAS 36051-31-7; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyCofactorsEnzyme SubstratesEnzymesInhibitorsand SubstratesG Protein FunctionGTPase

01 /Applications

Enzyme Assays and Substrates

Guanosine 5′-triphosphate sodium salt hydrate acts as a substrate in enzymatic reactions, particularly those involving GTPases. It is used to study enzyme kinetics and mechanisms in biochemical and cell biology research.

Cell Signaling Research

As a key signalling molecule, GTP is involved in various cellular pathways, including G protein-mediated signalling. This compound is essential for investigating cellular communication and signal transduction mechanisms.

Nucleic Acid Synthesis Research

While ATP is the primary substrate for RNA synthesis, GTP is also a necessary component, particularly for the initiation of transcription. Researchers use it to study RNA polymerase activity and gene expression.

Metabolomics Studies

This compound is a significant metabolite involved in various metabolic pathways. Its quantification and study are integral to metabolomics research for understanding cellular metabolic states.

02 /Properties

Molecular weight	523.18 (free acid basis)
Empirical formula	C10H16N5O14P3 · xNa+
Assay	≥95% (HPLC)
Form	powder
Colour	white
Solubility	H2O: soluble50 mg/mL
Concentration	100 mM in H2O (adjusted to pH 7)
Optical activity	[α]20/D −24±2°, c = 1% in 0.5 M Na2HPO4
Storage temperature	−20°C
Impurities tested	≤3 mol/mol water (NMR)

03 /Safety & handling

Protective equipment	Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

36051-31-7

MDL number

MFCD00077781

PubChem substance

24895354

Beilstein registry

3585677

05 /Additional specifications

Shipped In	dry ice
Gene Information	human ... HRAS(3265)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Guanosine 5′-triphosphate sodium salt hydrate used for?

It is used as a substrate in enzyme assays, particularly for GTPases, and as a signalling molecule in cell signalling research. It also plays a role in nucleic acid synthesis and is a key metabolite in metabolomics studies.

What are the CAS number and formula for Guanosine 5′-triphosphate sodium salt hydrate?

The CAS number is 36051-31-7, and the empirical formula is C10H16N5O14P3 · xNa+.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Guanosine 5′-triphosphate sodium salt hydrate with an assay of ≥95% (HPLC). It is a research-grade chemical and not represented as USP, BP, or EP.

How is this chemical handled and stored?

Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P1 (EN143) or N95 respirator filter. Store at -20°C. The product is shipped on dry ice.

Is this chemical shipped internationally by Tech Serve Solutions?

Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Guanosine 5′-triphosphate sodium salt hydrate, which is shipped on dry ice.