Grubbs Catalyst, 2nd Generation
Grubbs Catalyst, 2nd Generation (CAS: 246047-72-3), a Ruthenium-based carbine complex, is a highly effective catalyst for olefin metathesis reactions. With a molecular weight of 848.97 g/mol and formula C46H65Cl2N2PRu, it facilitates ring-closing metathesis (RCM), cross metathesis (CM), and ring-opening metathesis polymerization (ROMP). Its robust nature and broad functional group tolerance make it a preferred choice in synthetic organic chemistry and polymer science.
- IUPAC
- (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium,Benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(tricyclohexylphosphine)ruthenium,[1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium
- Synonyms
- C46H65Cl2N2PRu(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)rutheniumBenzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(tricyclohexylphosphine)ruthenium[1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium
Olefin Metathesis
Grubbs Catalyst, 2nd Generation is a cornerstone for various olefin metathesis reactions including RCM and CM. It efficiently produces trisubstituted olefins and demonstrates excellent selectivity.
Ring-Opening Metathesis Polymerization (ROMP)
This catalyst is instrumental in ROMP, enabling the synthesis of polymers with controlled structures. Its high activity and functional group tolerance are key advantages in polymerization processes.
Functional Group Tolerance in Synthesis
The catalyst exhibits remarkable tolerance to a wide range of functional groups, making it suitable for complex molecule synthesis where preserving sensitive functionalities is crucial.
| Molecular weight | 848.97 |
|---|---|
| Empirical formula | C46H65Cl2N2PRu |
| Storage temperature | 2-8°C |
| Application | Metathesis: Ruthenium-Based Metathesis CatalystsCatalyst for ring-closing metathesis, cross metathesis and ROMP1 able to produce trisubstituted olefins via cross metathesis,8 and ring closes olefins with excellent functional group tolerance and selectivity.9 |
| Melting point | 143.5-148.5 °C(lit.) |
Hazard statements
- H228Flammable solid
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F |
| Risk statements (R) | 11 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Grubbs Catalyst, 2nd Generation used for?
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Grubbs Catalyst, 2nd Generation is primarily used for olefin metathesis reactions such as ring-closing metathesis (RCM), cross metathesis (CM), and ring-opening metathesis polymerization (ROMP). It is valued for its high activity and broad functional group tolerance.
What are the CAS number and formula for Grubbs Catalyst, 2nd Generation?
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The CAS number for Grubbs Catalyst, 2nd Generation is 246047-72-3, and its empirical formula is C46H65Cl2N2PRu.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Grubbs Catalyst, 2nd Generation typically for research and development purposes. Please refer to the product's Certificate of Analysis for specific assay and purity details. TSS does not represent this product as USP, BP, or EP grade.
How should Grubbs Catalyst, 2nd Generation be handled and stored?
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Grubbs Catalyst, 2nd Generation is a flammable solid (H228) and requires careful handling. It should be stored at 2-8°C. Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator (type N95 or P1).
How is this product packed, shipped, and exported?
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Grubbs Catalyst, 2nd Generation is packed according to international shipping regulations for hazardous materials, identified as UN 1325, Class 4.1, PGII. Tech Serve Solutions is experienced in exporting chemicals globally.
How can I request a sample or quote for Grubbs Catalyst, 2nd Generation?
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To request a sample or a quote, please contact our sales team via the website or by phone. Our team will be happy to assist you with your inquiry.
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