Gambogic acid
Gambogic acid (CAS: 2752-65-0), a bioactive compound with the formula C38H44O8, is a yellow to orange powder known for its applications in biological research. Its primary utility lies in its capacity to induce apoptosis, making it a valuable tool in studies related to cell death, cell cycle regulation, and cancer research. Available from Tech Serve Solutions, it is supplied with an assay of ≥95% (HPLC).
- IUPAC
- 1,51,5-Methano-1H,3H,11H-furo(3,4-G)pyrano(3,2-B)xanthene-1-crotonic acid,B\"-Guttiferrin,Beta-Guttiferrin,Beta-Guttilactone,Cambogic acid,Guttatic acid,Guttic acid
- Synonyms
- 1,5,5-Methano-1H,3H,11H-furo(3,4-G)pyrano(3,2-B)xanthene-1-crotonic acidB-GuttiferrinBeta-GuttiferrinBeta-GuttilactoneCambogic acidGuttatic acidGuttic acid
Apoptosis Induction
Gambogic acid is recognized for its ability to trigger programmed cell death (apoptosis) in various cell lines. This makes it a key research chemical for investigating cellular defense mechanisms and developing therapeutic strategies against diseases characterized by uncontrolled cell proliferation.
Cell Cycle Regulation Studies
This compound plays a role in modulating the cell cycle. Researchers utilize Gambogic acid to understand the intricate pathways that govern cell division and to identify potential targets for anti-cancer drug development.
Bioactive Small Molecule Research
As a bioactive small molecule, Gambogic acid is employed in diverse biochemical and pharmacological studies. Its chemical structure and properties allow for exploration in various biological signaling pathways.
Phytochemical Research
Gambogic acid is a significant phytochemical found in traditional medicines. Its use in research contributes to understanding the medicinal properties of herbal extracts and developing new pharmaceuticals based on natural compounds.
| Empirical formula | C38H44O8 |
|---|---|
| Assay | ≥95% (HPLC) |
| Form | powder |
| Colour | yellow to orange |
| Solubility | DMSO: ≥10 mg/mLH2O: insoluble |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Gambogic acid used for?
+
Gambogic acid is primarily used in research as an apoptosis inducer and for studies related to cell cycle regulation and bioactive small molecules. It is also explored for its role as a phytochemical in traditional medicine.
What is the CAS number and formula for Gambogic acid?
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The CAS number for Gambogic acid is 2752-65-0, and its empirical formula is C38H44O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Gambogic acid with an assay of ≥95% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should Gambogic acid be handled safely?
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Gambogic acid is classified as toxic and an irritant. Handle with appropriate personal protective equipment including eyeshields, faceshields, gloves, and a P2 respirator cartridge. Avoid inhalation, ingestion, and contact with skin and eyes. Store at -20°C.
Is Gambogic acid a controlled substance?
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Based on the provided data, Gambogic acid is not indicated as a controlled substance.
How is Gambogic acid packed and shipped?
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Gambogic acid is shipped internationally as a hazardous material under UN 2811, Class 6.1, Packing Group III. Specific packaging details are available upon request.
How can I request a sample or quote for Gambogic acid?
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To request a sample or obtain a quote for Gambogic acid, please contact the Tech Serve Solutions sales team through our website or by phone.
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