Formic hydrazide
Formic hydrazide (CAS: 624-84-0) is an organic compound with the linear formula HCONHNH2 and a molecular weight of 60.06 g/mol. This white crystalline solid is known for its utility as a versatile building block in organic synthesis. It plays a key role in the creation of various heterocyclic compounds, including important triazole derivatives and complex molecules with potential biological activity, such as anticancer agents.
- IUPAC
- Formic acid hydrazide,Formylhydrazine
- Synonyms
- Formic acid hydrazideFormylhydrazine
Synthesis of Triazole Derivatives
Formic hydrazide serves as a crucial precursor in the synthesis of diverse 1,2,4-triazole derivatives, which are core structures in many pharmaceuticals and agrochemicals.
Anticancer Agent Synthesis
This compound has been employed in the development of novel anticancer agents, specifically contributing to the synthesis of complex polycyclic structures like 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7(6H)-dione.
Organic Synthesis Intermediate
As a readily available building block, formic hydrazide is widely used in general organic synthesis for constructing nitrogen-containing heterocyclic systems and other functionalised molecules.
| Molecular weight | 60.06 |
|---|---|
| Linear formula | HCONHNH2 |
| Solubility | water: soluble2.5%, clear, colorless |
| Application | Formic hydrazide was used in the synthesis of 1,2,4-triazole derivatives1. It was also used in the synthesis of new anticancer agent, 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7(6H)-dione2. |
| Melting point | 52-57 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 112 °C / 233.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Formic hydrazide used for?
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Formic hydrazide is primarily used as a building block in organic synthesis, particularly for the preparation of 1,2,4-triazole derivatives and complex molecules such as potential anticancer agents.
What is the CAS number and formula for Formic hydrazide?
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The CAS number for Formic hydrazide is 624-84-0, and its linear formula is HCONHNH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Formic hydrazide as a technical/research grade chemical. We do not represent it as meeting USP, BP, or EP pharmacopoeia standards. Please refer to the product specifications for available purity information.
What are the safety precautions for handling Formic hydrazide?
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Formic hydrazide is classified with a Warning signal word, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always use appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Handle in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
How is Formic hydrazide packed and exported?
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Formic hydrazide is carefully packed to ensure stability and safety during transit. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals.
How can I request a sample or quote for Formic hydrazide?
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To request a sample or a quote for Formic hydrazide, please use the contact form on our website or reach out to our sales team directly.
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