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Ethylphosphonic dichloride

CAS 1066-50-8C2H5P(O)Cl2Chemical Synthesis

Ethylphosphonic dichloride (CAS: 1066-50-8, Formula: C2H5P(O)Cl2) is a phosphorus halide compound with a molecular weight of 146.94 g/mol. It is a key intermediate in organic synthesis, particularly useful for introducing the ethylphosphonyl group. This reagent is employed in the preparation of various organophosphorus compounds, including phosphonates and phosphonic derivatives, serving as a valuable building block in chemical research and development.

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Ethylphosphonic dichloride (C2H5P(O)Cl2) — chemical structure, CAS 1066-50-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisOrganic Building BlocksPhosphorus CompoundsPhosphorus Halides
01 /Applications

Preparation of Ethylphosphonic Diisocyanate

Ethylphosphonic dichloride serves as a precursor in the synthesis of ethylphosphonic diisocyanate. This transformation is a crucial step for generating isocyanate-containing organophosphorus compounds with potential applications in materials science and chemical synthesis.

Synthesis of Substituted Ethylphosphonates

This compound is utilised in reactions to produce various substituted ethylphosphonates, such as 4-acetylphenyl isopropyl ethylphosphonate. These derivatives can be explored for their unique chemical properties and potential uses in organic chemistry.

Intermediate for Organophosphorus Chemistry

As a versatile building block, ethylphosphonic dichloride is instrumental in constructing more complex organophosphorus molecules. Its reactivity allows for the controlled introduction of the ethylphosphonyl moiety into diverse chemical structures.

02 /Properties
Molecular weight146.94
Linear formulaC2H5P(O)Cl2
Assay98%
Boiling point71-72 °C/12 mmHg(lit.)
Density1.376 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.465(lit.)
ApplicationEthylphosphonic dichloride has been used in the preparation of:• ethylphosphonic diisocyanate1• 4-acetylphenyl isopropyl ethylphosphonate2• 4-acetylphenyl phenyl ethylphosphonate2• 4-acetylphenyl cyclohexyl ethylphosphonate2
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H300Fatal if swallowed
  • H311Toxic in contact with skin
  • H314Causes severe skin burns and eye damage
  • H331Toxic if inhaled

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P264Wash thoroughly after handling
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point113 °C / 235.4 °F
Transport (UN / ADR)UN 2922 8/PG 2
Water hazard class (WGK, DE)3
Hazard codes (EU)T
Risk statements (R)23/24/25-34
Safety statements (S)23-26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
1066-50-8
MDL number
MFCD00002073
PubChem substance
24856684
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Ethylphosphonic dichloride used for?

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Ethylphosphonic dichloride is used as a building block in organic synthesis, primarily for preparing ethylphosphonic diisocyanate and various substituted ethylphosphonates. It is a valuable intermediate in organophosphorus chemistry.

What is the CAS number and formula for Ethylphosphonic dichloride?

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The CAS number for Ethylphosphonic dichloride is 1066-50-8, and its linear formula is C2H5P(O)Cl2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Ethylphosphonic dichloride with a minimum purity of 98%. This product is intended for laboratory and research purposes. TSS does not represent this chemical as USP, BP, or EP grade.

How should Ethylphosphonic dichloride be handled safely?

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Ethylphosphonic dichloride is a dangerous substance, classified with GHS05 and GHS06 symbols, and carries the signal word 'Danger'. It is acutely toxic if swallowed, in contact with skin, and if inhaled, and causes severe skin burns and eye damage. Always handle with appropriate personal protective equipment, including gloves, goggles, a faceshield, and a suitable respirator, in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling information.

Can I request a sample or quote for Ethylphosphonic dichloride?

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Yes, you can request a sample or a quote for Ethylphosphonic dichloride. Please contact our sales team through the website or by phone to discuss your requirements.

How is Ethylphosphonic dichloride shipped?

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Ethylphosphonic dichloride is shipped as a hazardous material under UN 2922, Class 8/PG 2. All shipments comply with international regulations for the transport of dangerous goods.

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