Ethyl piperazinoacetate
Ethyl piperazinoacetate (CAS: 40004-08-8; Formula: C8H16N2O2; MW: 172.22) is a chemical compound supplied by Tech Serve Solutions. It serves as a valuable intermediate in various chemical synthesis pathways, particularly within the realms of chemical biology and peptide chemistry. Its structure, featuring both piperazine and acetate ester functionalities, allows for diverse reactivity, making it a useful building block in organic chemistry research and development.
- IUPAC
- 1-(Ethoxycarbonylmethyl)piperazine,N-(Carboethoxymethyl)-piperazine,Ethyl 1-piperazineacetate
- Synonyms
- 1-(Ethoxycarbonylmethyl)piperazineN-(Carboethoxymethyl)-piperazineEthyl 1-piperazineacetate

Chemical Synthesis
Utilised as a key building block in the synthesis of more complex organic molecules. Its bifunctional nature allows for selective reactions at either the piperazine nitrogen or the ester group.
Peptide Chemistry
A valuable reagent in the preparation of modified peptides and peptidomimetics. It can be incorporated to introduce specific structural features or functionalities into peptide chains.
Chemical Biology Research
Employed in the development of novel chemical probes and biologically active compounds for research purposes. Its unique structure lends itself to exploring structure-activity relationships.
Unnatural Amino Acid Derivatives
Serves as a precursor for the synthesis of unnatural amino acid derivatives, expanding the scope of amino acid chemistry for pharmaceutical and biochemical applications.
| Molecular weight | 172.22 |
|---|---|
| Empirical formula | C8H16N2O2 |
| Assay | ≥95.0% (GC) |
| Density | 1.048 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.472 |
| Storage temperature | −20°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl piperazinoacetate used for?
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Ethyl piperazinoacetate is primarily used as an intermediate in chemical synthesis, particularly in peptide chemistry and the development of unnatural amino acid derivatives for research in chemical biology.
What is the CAS number and formula for Ethyl piperazinoacetate?
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The CAS number for Ethyl piperazinoacetate is 40004-08-8, and its molecular formula is C8H16N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl piperazinoacetate with a minimum purity of 95.0% (GC). This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or any pharmacopoeia grade.
How should Ethyl piperazinoacetate be handled and stored?
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Ethyl piperazinoacetate is classified as a warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It should be handled with appropriate personal protective equipment, including eyeshields and gloves, in a well-ventilated area. Recommended storage is at -20°C.
Is Ethyl piperazinoacetate a controlled substance?
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The provided data does not indicate that Ethyl piperazinoacetate (CAS: 40004-08-8) is a controlled substance.
How is Ethyl piperazinoacetate packed and shipped?
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Tech Serve Solutions professionally packs and exports fine chemicals globally. Specific packaging details for Ethyl piperazinoacetate will be provided upon order confirmation, adhering to all relevant shipping regulations.
How can I request a sample or quote for Ethyl piperazinoacetate?
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To request a sample or a quotation for Ethyl piperazinoacetate, please contact our sales team through the provided channels on the Tech Serve Solutions website.
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