Ethyl p-tolylacetate
Ethyl p-tolylacetate (CAS: 14062-19-2; Formula: CH3C6H4CH2CO2C2H5) is a chemical compound with a molecular weight of 178.23 g/mol. This ester, characterised by its p-tolyl and ethyl acetate moieties, serves as a valuable intermediate and building block in organic synthesis. Its applications are primarily focused on the preparation of more complex organic molecules, including specific phenylpropioloylacetates and potential antifungal agents.
Synthesis of Phenylpropioloylacetates
Ethyl p-tolylacetate has been employed in synthetic routes leading to ethyl-substituted phenylpropioloylacetates. These reactions leverage the reactive ester and aromatic functionalities of the molecule for further elaboration.
Preparation of Halogenated Intermediates
The compound is utilised in the synthesis of intermediates such as ethyl 2-(4-bromomethylphenyl)propionate. This highlights its role in constructing functionalised aromatic systems.
Antifungal Agent Precursor
Ethyl p-tolylacetate has been identified as a precursor in the synthesis of (-)-incrustoporin, a natural product exhibiting antifungal properties. This points to its relevance in medicinal chemistry research.
| Molecular weight | 178.23 |
|---|---|
| Linear formula | CH3C6H4CH2CO2C2H5 |
| Assay | 98% |
| Boiling point | 116-118 °C/13 mmHg(lit.) |
| Density | 1.008 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.496(lit.) |
| Application | Ethyl p-tolylacetate was used in preparation of:• ethyl-substituted phenylpropioloylacetates1• ethyl 2-(4-bromomethylphenyl)propionate2• (-)-incrustoporin, antifungal agent3 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 109 °C / 228.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl p-tolylacetate used for?
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Ethyl p-tolylacetate is used as a building block and intermediate in organic synthesis. It has been specifically applied in the preparation of ethyl-substituted phenylpropioloylacetates, ethyl 2-(4-bromomethylphenyl)propionate, and (-)-incrustoporin, an antifungal agent.
What are the CAS number and formula for Ethyl p-tolylacetate?
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The CAS number for Ethyl p-tolylacetate is 14062-19-2, and its chemical formula is CH3C6H4CH2CO2C2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl p-tolylacetate with a minimum purity of 98%. This product is typically supplied for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should Ethyl p-tolylacetate be handled?
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Ethyl p-tolylacetate is classified as a warning substance, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, such as eyeshields and gloves, should be worn. Ensure adequate ventilation, and use a suitable respirator if necessary. Refer to the Safety Data Sheet (SDS) for detailed handling instructions.
Is Ethyl p-tolylacetate a controlled substance?
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The provided data does not indicate that Ethyl p-tolylacetate (CAS: 14062-19-2) is a controlled substance.
How can I request a quote or sample for Ethyl p-tolylacetate?
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To request a quote or a sample of Ethyl p-tolylacetate, please contact our sales team via the website or by phone. Provide the product name and CAS number (14062-19-2) for prompt service.
How is Ethyl p-tolylacetate packed and exported?
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Tech Serve Solutions expertly packs and exports chemicals globally, adhering to all relevant shipping regulations. Specific packing details can be provided upon request when placing an order.
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