Ethyl α-bromoisobutyrate
Ethyl α-bromoisobutyrate (CAS: 600-00-0) is an organic ester with the linear formula (CH3)2CBrCOOC2H5 and a molecular weight of 195.05 g/mol. This compound serves as a key initiator in Atom Transfer Radical Polymerization (ATRP), enabling controlled polymer synthesis with specific end-group functionality. It is widely utilised as a building block in organic synthesis and materials science research.
- IUPAC
- Ethyl 2-bromo-2-methylpropionate
- Synonyms
- Ethyl 2-bromo-2-methylpropanoate

Atom Transfer Radical Polymerization (ATRP) Initiator
Ethyl α-bromoisobutyrate functions as an effective initiator for ATRP. It facilitates the controlled synthesis of polymers, introducing an ethyl end group into the polymer chain.
Organic Synthesis Building Block
This compound is a valuable intermediate in the synthesis of various organic molecules. Its reactive bromine atom allows for further functionalisation in complex synthetic pathways.
Materials Science Research
Utilised in the development of novel polymeric materials, Ethyl α-bromoisobutyrate contributes to the precise control over polymer architecture and properties.
| Molecular weight | 195.05 |
|---|---|
| Linear formula | (CH3)2CBrCOOC2H5 |
| Assay | 98% |
| Boiling point | 65-67 °C/11 mmHg(lit.) |
| Density | 1.329 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.444(lit.) |
| Application | Atom Transfer Radical Polymerization (ATRP) initiator that will generate a polymer with an ethyl end group. |



Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 60 °C / 140 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl α-bromoisobutyrate used for?
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Ethyl α-bromoisobutyrate is primarily used as an initiator for Atom Transfer Radical Polymerization (ATRP) and as a building block in organic synthesis and materials science research.
What are the CAS number and formula for Ethyl α-bromoisobutyrate?
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The CAS number for Ethyl α-bromoisobutyrate is 600-00-0, and its linear formula is (CH3)2CBrCOOC2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl α-bromoisobutyrate with an assay of 98%. This product is not represented as USP, BP, or EP grade.
What are the safety considerations for handling Ethyl α-bromoisobutyrate?
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Ethyl α-bromoisobutyrate is a Danger hazard (GHS02, GHS05, GHS07) due to flammability and risk of serious eye damage, and is harmful if swallowed. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area, away from ignition sources.
How is Ethyl α-bromoisobutyrate packed, shipped, and exported?
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Tech Serve Solutions expertly packs, handles, and exports chemicals globally, adhering to all relevant shipping regulations for hazardous materials like Ethyl α-bromoisobutyrate (UN 1993, Class 3).
How can I request a quote or sample of Ethyl α-bromoisobutyrate?
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To request a quote or sample of Ethyl α-bromoisobutyrate, please contact our sales team through the website or by phone.
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