Ethyl 4-fluorobenzoate
Ethyl 4-fluorobenzoate (CAS 451-46-7), with the molecular formula FC6H4CO2C2H5 and a molecular weight of 168.16 g/mol, is a fluorinated aromatic ester. It serves as a valuable building block in organic synthesis. This compound is primarily utilised in chemical research and development, particularly in the creation of more complex fluorinated organic molecules and pharmaceutical intermediates.
Synthesis of Piperazine Derivatives
Ethyl 4-fluorobenzoate can be employed as a precursor in the synthesis of specific piperazine derivatives, such as 4,4′-(1,4-Piperazinediyl) bisbenzoic acid ethyl ester, contributing to the development of specialised chemical compounds.
Organic Synthesis Building Block
As a fluorinated aromatic ester, it is a versatile reagent in organic chemistry for introducing the 4-fluorobenzoyl moiety into target molecules. Its structure makes it useful for developing new materials and fine chemicals.
Research and Development
This compound is utilised in laboratory settings for research purposes, enabling chemists to explore novel reaction pathways and construct complex organic architectures incorporating fluorine.
| Molecular weight | 168.16 |
|---|---|
| Linear formula | FC6H4CO2C2H5 |
| Assay | 99% |
| Boiling point | 210 °C(lit.) |
| Density | 1.146 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.486(lit.) |
| Application | Ethyl 4-fluorobenzoate may be used in the synthesis of 4,4′-(1,4-Piperazinediyl) bisbenzoic acid ethyl ester1. |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 81 °C / 177.8 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 4-fluorobenzoate used for?
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Ethyl 4-fluorobenzoate is used as a building block in organic synthesis, particularly for creating fluorinated organic molecules and pharmaceutical intermediates. It has been used in the synthesis of 4,4′-(1,4-Piperazinediyl) bisbenzoic acid ethyl ester.
What are the CAS number and chemical formula for Ethyl 4-fluorobenzoate?
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The CAS number is 451-46-7 and the linear chemical formula is FC6H4CO2C2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 4-fluorobenzoate with a purity of 99%. We do not represent this product as USP, BP, or EP grade; it is supplied for research and development purposes.
How should Ethyl 4-fluorobenzoate be handled safely?
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Handling should be done with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a respirator if necessary, as indicated by safety data. It is combustible, with a flash point of 81 °C (177.8 °F).
Is Ethyl 4-fluorobenzoate controlled or scheduled?
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The provided data does not indicate that Ethyl 4-fluorobenzoate is a controlled or scheduled substance.
How is Ethyl 4-fluorobenzoate packed and exported?
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Tech Serve Solutions exports chemicals globally, adhering to all necessary shipping and customs regulations. Specific packing details depend on the quantity and destination.
How can I request a quote or sample for Ethyl 4-fluorobenzoate?
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To request a quote or sample, please contact our sales team through the TSS website or by phone, referencing the product name and CAS number 451-46-7.
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