Ethyl (2-bromobenzoyl)acetate
Ethyl (2-bromobenzoyl)acetate (CAS: 50671-05-1) is an organic compound with the linear formula BrC₆H₄COCH₂CO₂C₂H₅ and a molecular weight of 271.11 g/mol. This ester and carbonyl compound serves as a valuable intermediate in organic synthesis. It is primarily utilised as a reactant for the preparation of complex molecules, including sirtuin inhibitors, quinolones, indoles, and various enamine derivatives, making it a key building block for pharmaceutical and chemical research.
Synthesis of Sirtuin Inhibitors
Ethyl (2-bromobenzoyl)acetate is employed as a precursor in the synthesis of Cambinol analogs. These compounds have demonstrated potential as sirtuin inhibitors with notable antitumor activity, contributing to cancer research.
Preparation of Quinolones and Indoles
This compound functions as a reactant in cyclodehydration reactions, facilitating the formation of quinolone and indole ring systems. These heterocyclic structures are significant scaffolds in medicinal chemistry.
Generation of N-Allyl/Propargyl Enamine Carboxylates
It is used in synthetic routes to produce N-allyl or N-propargyl enamine carboxylates. These intermediates offer versatile functional groups for further chemical transformations and molecular construction.
| Molecular weight | 271.11 |
|---|---|
| Linear formula | BrC6H4COCH2CO2C2H5 |
| Assay | ≥95% |
| Density | 1.417 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5545(lit.) |
| Application | Reactant for preparation of:• Cambinol analogs as sirtuin inhibitors with antitumor action1• Quinolones and indoles by cyclodehydration2• N-allyl/propargyl enamine carboxylates3 |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl (2-bromobenzoyl)acetate used for?
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Ethyl (2-bromobenzoyl)acetate is used as a reactant in organic synthesis, particularly for preparing Cambinol analogs (sirtuin inhibitors), quinolones, indoles, and N-allyl/propargyl enamine carboxylates.
What is the CAS number and molecular formula for Ethyl (2-bromobenzoyl)acetate?
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The CAS number is 50671-05-1, and the linear formula is BrC₆H₄COCH₂CO₂C₂H₅.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl (2-bromobenzoyl)acetate with an assay of ≥95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated. It is supplied for research and development purposes.
What are the safety and handling precautions for Ethyl (2-bromobenzoyl)acetate?
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According to safety data, Ethyl (2-bromobenzoyl)acetate is classified under WGK Germany 3. When handling, it is essential to use appropriate personal protective equipment, including eyeshields and gloves, to minimise exposure.
Is Ethyl (2-bromobenzoyl)acetate a controlled substance?
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Based on the provided data, there is no indication that Ethyl (2-bromobenzoyl)acetate is a controlled substance.
How are chemicals like Ethyl (2-bromobenzoyl)acetate packed and shipped?
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Tech Serve Solutions ensures that all products, including Ethyl (2-bromobenzoyl)acetate, are packed and shipped in compliance with international regulations for hazardous materials, suitable for global export.
How can I request a quote or sample for Ethyl (2-bromobenzoyl)acetate?
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To request a quote or a sample of Ethyl (2-bromobenzoyl)acetate, please contact our sales department through the website or by phone. Our team will assist you promptly.
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