Ethyl 1-bromocyclobutanecarboxylate
Ethyl 1-bromocyclobutanecarboxylate (CAS: 35120-18-4) is an organic compound with the formula BrC4H6CO2C2H5 and a molecular weight of 207.07 g/mol. It functions as a valuable building block in organic synthesis. This ester is primarily utilised in the preparation of other complex molecules, notably contributing to the synthesis of amino acid derivatives. Supplied by TSS, it is available at 96% purity for research and development purposes.

Synthesis of Amino Acid Derivatives
Ethyl 1-bromocyclobutanecarboxylate serves as a key intermediate in the synthesis of cyclobutane-containing amino acids, such as 1-aminocyclobutane carboxylic acid. This application is crucial in medicinal chemistry for developing novel therapeutic agents.
Organic Building Block
As a versatile organic building block, this compound can be employed in various carbon-carbon bond-forming reactions. Its structure allows for diverse synthetic transformations, making it useful in the development of new chemical entities.
Chemical Synthesis Reagent
The presence of the reactive bromine atom and the ester functional group enables Ethyl 1-bromocyclobutanecarboxylate to participate in a range of chemical reactions. It is utilized in multi-step syntheses within academic and industrial research laboratories.
| Molecular weight | 207.07 |
|---|---|
| Linear formula | BrC4H6CO2C2H5 |
| Assay | 96% |
| Boiling point | 85-88 °C/12 mmHg(lit.) |
| Density | 1.279 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.471(lit.) |
| Storage temperature | 2-8°C |
| Application | Ethyl 1-bromocyclobutanecarboxylate was used in the synthesis of 1−aminocyclobutane carboxylic acid1. |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 1-bromocyclobutanecarboxylate used for?
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Ethyl 1-bromocyclobutanecarboxylate is primarily used as a building block in organic synthesis, notably in the preparation of 1-aminocyclobutane carboxylic acid and other cyclobutane derivatives.
What is the CAS number and chemical formula for Ethyl 1-bromocyclobutanecarboxylate?
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The CAS number is 35120-18-4 and the chemical formula is BrC4H6CO2C2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl 1-bromocyclobutanecarboxylate at a purity of 96%. It is suitable for research and development purposes. TSS does not represent this product as USP, BP, or EP grade.
How should Ethyl 1-bromocyclobutanecarboxylate be handled and stored?
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This compound is classified as corrosive (H314) and requires careful handling. It should be stored at 2-8°C and appropriate personal protective equipment, including gloves, goggles, a face shield, and a suitable respirator, must be worn when handling. Refer to the safety data sheet for detailed guidance.
Is Ethyl 1-bromocyclobutanecarboxylate a controlled substance?
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The provided data does not indicate that Ethyl 1-bromocyclobutanecarboxylate is a controlled substance.
How can I request a sample or quote for Ethyl 1-bromocyclobutanecarboxylate?
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To request a sample or a quote, please contact the TSS sales department through our website or by phone, providing the product name and CAS number (35120-18-4).
How is Ethyl 1-bromocyclobutanecarboxylate packaged and exported?
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Ethyl 1-bromocyclobutanecarboxylate is packaged according to safety regulations for corrosive materials (UN 3265 8 / PGII) and exported globally by TSS, adhering to all relevant international shipping standards.
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