Ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride
Ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride (CAS 52763-21-0), with the molecular formula C15H19NO3 · HCl and a molecular weight of 297.78 g/mol, is a heterocyclic building block. This piperidone derivative is valuable in organic synthesis for constructing complex molecular architectures, particularly in the development of novel pharmaceutical compounds and research chemicals.
- IUPAC
- 1-Benzyl-4-ethoxycarbonyl-3-piperidone hydrochloride
Synthesis of Chromeno[3,4-c]pyridin-5-ones
Ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride serves as a key intermediate in the multi-step synthesis of chromeno[3,4-c]pyridin-5-one derivatives, contributing to the exploration of novel heterocyclic scaffolds.
Development of Receptor Agonists and Antagonists
This compound acts as a crucial building block in the synthesis pathways aimed at creating receptor agonists and antagonists, which are vital for pharmacological research and drug discovery.
Precursor for Benzamide Derivatives
It functions as a starting reagent in the synthesis of complex benzamide derivatives, such as 4-amino-5-chloro-2-methoxy-N-[1-[5-(1-methylindol-3-ylcarbonylamino)pentyl]piperidin-4-ylmethyl]benzamide, demonstrating its utility in creating diverse molecular structures.
| Molecular weight | 297.78 |
|---|---|
| Empirical formula | C15H19NO3 · HCl |
| Grade | technical grade |
| Solubility | NH4OH: soluble25 mg/mL, clear, yellow ((Methanol)) |
| Application | Ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride was used in the synthesis of chromeno[3,4-c]pyridin-5-ones1. It was used as building block for the syntheses of receptor agonists and antagonists2,3. It was used as starting reagent in the synthesis of 4-amino-5-chloro-2-methoxy-N-[1-[5-(1-methylindol-3-ylcarbonylamino)pentyl]piperidin-4-ylmethyl]benzamide derivative4. |
| Melting point | 162 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride used for?
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Ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride is used as a building block in organic synthesis, including the preparation of chromeno[3,4-c]pyridin-5-ones, receptor agonists and antagonists, and complex benzamide derivatives.
What is the CAS number and molecular formula?
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The CAS number is 52763-21-0, and the molecular formula is C15H19NO3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound in technical grade. We do not represent it as USP, BP, or EP grade.
How should Ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride be handled?
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This compound is a warning substance and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use a dust mask type N95, eyeshields, and gloves. Ensure adequate ventilation.
Is this compound a controlled substance?
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The provided data does not indicate that Ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride is a controlled substance.
How is this chemical supplied and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents. Specific packing and shipping details are available upon request.
How can I request a sample or quote?
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To request a sample or quote for Ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate hydrochloride, please contact the Tech Serve Solutions sales team via our website or direct enquiry channels.
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