Estrone
Estrone (CAS: 53-16-7), with the molecular formula C18H22O2 and a molecular weight of 270.37 g/mol, is a steroid compound. It is a naturally occurring oestrogen and a key intermediate in oestrogen biosynthesis. Estrone is utilised in biochemical research and as an analytical standard, particularly in areas concerning hormone analysis and endocrinology.
- IUPAC
- 1,3,5(10)-Estratrien-3-ol-17-one,3-Hydroxy-1,3,5(10)-estratrien-17-one,Folliculin
- Synonyms
- 1,3,5(10)-Estratrien-3-ol-17-one3-Hydroxy-1,3,5(10)-estratrien-17-oneFolliculin

Biochemical Research
Estrone serves as a valuable tool in biochemical and endocrinological research, enabling studies into steroid hormone metabolism and receptor interactions.
Analytical Standard
Utilised as a reference standard in chromatography and other analytical techniques for the accurate quantification of oestrogens in biological samples.
Steroid Metabolism Studies
Its role as a precursor and metabolite makes it essential for investigating complex pathways of steroid hormone synthesis and breakdown within biological systems.
| Molecular weight | 270.37 |
|---|---|
| Empirical formula | C18H22O2 |
| Suitability | meets USP testing specifications |
| Melting point | 258-260 °C(lit.) |

Hazard statements
- H350May cause cancer
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-60-61 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ESR1(2099), ESR2(2100), ESRRA(2101), ESRRB(2103), HSD17B1(3292), SERPINA6(866)mouse ... Esr1(13982)rat ... Esr1(24890) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Estrone (CAS 53-16-7) used for?
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Estrone is used in biochemical research, as an analytical standard for hormone analysis, and for studies into steroid metabolism and oestrogen pathways.
What is the CAS number and chemical formula for Estrone?
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The CAS number for Estrone is 53-16-7, and its chemical formula is C18H22O2.
What grade and purity does Tech Serve Solutions supply for Estrone?
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Tech Serve Solutions supplies Estrone that meets USP testing specifications. Please contact us for specific lot purity details or certificates of analysis, as TSS does not represent this product as USP/BP/EP grade unless explicitly stated for the specific batch.
How should Estrone be handled safely?
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Estrone is labelled with hazard statements H350 (May cause cancer) and H360 (May damage fertility or the unborn child). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a P2 respirator. Ensure good ventilation and follow all safety protocols.
Is Estrone a controlled substance?
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The provided data does not indicate that Estrone is a controlled substance. However, users should verify local regulations.
How can I request a sample or quote for Estrone?
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To request a sample or a quote for Estrone, please contact the Tech Serve Solutions sales team via our website or by calling us directly.
How is Estrone packed and shipped?
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Estrone is carefully packed according to international shipping regulations for chemicals and exported globally by Tech Serve Solutions.
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