Estrone 3-sulfate sodium salt
Estrone 3-sulfate sodium salt (CAS: 438-67-5, C18H21O5SNa) is a bioactive small molecule. As a stable, water-soluble sulfate conjugate of estrone, it serves as a research tool in areas such as cell biology, cell signaling, and neuroscience. It functions as a steroid hormone, specifically an estrogen. Its utility lies in biochemical and physiological studies investigating hormonal pathways and related cellular responses. TSS offers this compound for laboratory and research applications.
- IUPAC
- 1,3,5(10)-Estratrien-17-one 3-sulfate

Endocrine Research
Used in studies investigating estrogenic activity and hormonal regulation. Its soluble nature facilitates in vitro and in vivo research into the endocrine system.
Cell Signaling Studies
Serves as a tool for examining cellular responses to estrogenic stimuli. Applicable in research focused on cell communication and hormonal pathways.
Neuroscience Research
Investigates the role of estrogens in neurological processes. Useful for understanding how hormones influence neuronal function and behaviour.
Biochemical Assays
Applied in biochemical investigations requiring a well-defined estrogenic compound. Its defined structure and stability are advantageous for assay development.
| Molecular weight | 372.41 |
|---|---|
| Linear formula | C18H21O5SNa |
| Storage temperature | −20°C |
| Contains / stabiliser | ~35% Tris as stabilizer |


Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P308IF exposed or concerned
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | T |
| Risk statements (R) | 45-36/37/38 |
| Safety statements (S) | 53-26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Estrone 3-sulfate sodium salt used for?
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Estrone 3-sulfate sodium salt is used in biochemical and physiological research, particularly in studies of cell biology, cell signaling, neuroscience, and endocrine functions, serving as a bioactive small molecule and an estrogen.
What is the CAS number and chemical formula for Estrone 3-sulfate sodium salt?
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The CAS number is 438-67-5, and the chemical formula is C18H21O5SNa.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Estrone 3-sulfate sodium salt primarily for research and laboratory use. The specific grade and purity are detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or for pharmaceutical, nutraceutical, or food applications unless explicitly stated.
What are the primary safety hazards associated with Estrone 3-sulfate sodium salt?
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This compound carries significant hazards, indicated by GHS07 and GHS08 symbols, with a Danger signal word. It is associated with hazards including skin irritation (H315), serious eye irritation (H319), respiratory irritation (H335), and potential carcinogenicity (H350). Always handle with appropriate personal protective equipment in a well-ventilated area, and refer to the Safety Data Sheet.
How is Estrone 3-sulfate sodium salt packed, shipped, and exported?
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Estrone 3-sulfate sodium salt is typically stored at -20°C. TSS ensures careful packing and adherence to international shipping regulations for chemical exports, providing necessary documentation for global distribution.
How can I request a quote or sample for Estrone 3-sulfate sodium salt?
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To request a quote or sample, please visit the Tech Serve Solutions website and use the contact form or product inquiry tool, referencing the product name and CAS number.
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