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β-Estradiol

CAS 50-28-2C18H24O2Chemical Synthesis

β-Estradiol (CAS: 50-28-2, C18H24O2) is a key steroid hormone with a molecular weight of 272.38 g/mol. Known for its role in biological systems, it is also a valuable compound in chemical synthesis and cell biology research. This high-purity chemical is suitable for cell culture applications, making it a critical reagent for scientific investigation. Tech Serve Solutions supplies β-Estradiol for various research and synthesis needs.

IUPAC
1,3,5-Estratriene-3,17β-diol,17β-Estradiol,3,17β-Dihydroxy-1,3,5(10)-estratriene,Dihydrofolliculin
Synonyms
1,3,5-Estratriene-3,17β-diol17β-Estradiol3,17β-Dihydroxy-1,3,5(10)-estratrieneDihydrofolliculin
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β-Estradiol (C18H24O2) — chemical structure, CAS 50-28-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisCell BiologyChemical SynthesisChiral Building BlocksComplex MoleculesHumulus lupulus (Hops)Nutrition ResearchPanax ginseng
01 /Applications

Asymmetric Synthesis and Chiral Building Blocks

Utilised as a chiral building block in asymmetric synthesis, β-Estradiol's defined stereochemistry is valuable for constructing complex molecules with precise three-dimensional structures.

Cell Biology Research

Its biological significance makes it an important tool in cell biology studies, particularly in research related to hormone-dependent cellular processes and signalling pathways.

Chemical Synthesis

Serves as a starting material or intermediate in the synthesis of various organic compounds, leveraging its steroid backbone for further chemical modifications.

Nutrition and Phytochemical Research

Found in sources like Humulus lupulus, it is studied in the context of phytochemicals and their roles, including within nutrition research.

02 /Properties
Molecular weight272.38
Empirical formulaC18H24O2
Assay≥97.0% (HPLC)
Gradepurum
Optical activity[α]20/D +79±2°, c = 1% in dioxane
Suitabilitysuitable for cell culture
Melting point176-180 °C(lit.)176-180 °C
03 /Safety & handling
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
Danger

Hazard statements

  • H351Suspected of causing cancer
  • H360FD
  • H362May cause harm to breast-fed children

Precautionary statements

  • P201Obtain special instructions before use
  • P263
  • P281Use personal protective equipment as required
  • P308IF exposed or concerned
Protective equipmentEyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Water hazard class (WGK, DE)3
Hazard codes (EU)T
Risk statements (R)60-63-40-64
Safety statements (S)53-45176-180 °C

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
50-28-2
MDL number
MFCD00003693
Beilstein registry
1914275
05 /Additional specifications
Potency0.2-10 ng/mL
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is β-Estradiol primarily used for?

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β-Estradiol is used in chemical synthesis, as a chiral building block, and in cell biology research, particularly for studies involving hormone-dependent processes.

What are the CAS number and molecular formula for β-Estradiol?

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The CAS number for β-Estradiol is 50-28-2, and its molecular formula is C18H24O2.

What grade and purity does Tech Serve Solutions supply for β-Estradiol?

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Tech Serve Solutions supplies β-Estradiol with a purity of ≥97.0% (HPLC) and a 'purum' grade, suitable for cell culture. It is not represented as USP, BP, or EP grade unless explicitly stated.

How should β-Estradiol be handled safely?

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Handle β-Estradiol with appropriate personal protective equipment, including eyeshields and gloves. Due to its hazardous nature (H351, H360Fd, H362), use a respirator and follow all safety instructions, especially regarding carcinogenic, mutagenic, and reproductive toxicity.

Is β-Estradiol a controlled substance?

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Based on the provided data, β-Estradiol is classified with hazard codes T (Toxic) in Europe and carries significant health hazard statements. Users should verify local regulations regarding its handling and control status.

How is β-Estradiol packed and shipped?

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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and shipping for β-Estradiol, adhering to international regulations for chemical transport.

How can I request a quote or sample for β-Estradiol?

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To request a quote or sample of β-Estradiol, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.

Need β-Estradiol in a specific grade or volume?