DL-3,5-Difluorophenylalanine
DL-3,5-Difluorophenylalanine (CAS: 32133-37-2) is a synthetic unnatural amino acid derivative with a molecular weight of 201.17 g/mol. Characterised by the presence of two fluorine atoms on the phenyl ring, it is a valuable building block in chemical synthesis and peptide chemistry. Its unique structure allows for the introduction of fluorinated moieties into peptides and small molecules, impacting their properties and functions.
- Synonyms
- F2C6H3CH2CH(NH2)CO2H

Chemical Synthesis Intermediate
Utilised as a specialised intermediate in the synthesis of complex organic molecules and pharmaceuticals. The difluorophenyl group can impart desirable characteristics such as enhanced metabolic stability or altered binding affinities.
Peptide Chemistry and Drug Discovery
Incorporated into peptides to create novel analogues with modified biological activities. It is a key component in the development of peptidomimetics and fluorinated drug candidates.
Chemical Biology Research
Employed in chemical biology studies to investigate protein structure-function relationships and probe biological systems. Its unnatural structure can serve as a reporter or to modulate biomolecular interactions.
| Molecular weight | 201.17 |
|---|---|
| Linear formula | F2C6H3CH2CH(NH2)CO2H |
| Assay | 97% |
| Melting point | 269.5-273.5 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is DL-3,5-Difluorophenylalanine used for?
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DL-3,5-Difluorophenylalanine is used as an intermediate in chemical synthesis, particularly in peptide chemistry and drug discovery. It is also applied in chemical biology research to create novel fluorinated molecules and peptides.
What is the CAS number and chemical formula for DL-3,5-Difluorophenylalanine?
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The CAS number for DL-3,5-Difluorophenylalanine is 32133-37-2. Its linear formula is F₂C₆H₃CH₂CH(NH₂)CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies DL-3,5-Difluorophenylalanine with an assay of 97%. This product is intended for research and laboratory use. Tech Serve Solutions does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should DL-3,5-Difluorophenylalanine be handled safely?
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Handling DL-3,5-Difluorophenylalanine requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Refer to the safety data sheet for comprehensive handling instructions.
How is DL-3,5-Difluorophenylalanine shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including DL-3,5-Difluorophenylalanine, adhering to all necessary international shipping and export regulations.
How can I request a sample or quote for DL-3,5-Difluorophenylalanine?
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To request a sample or a quote for DL-3,5-Difluorophenylalanine, please contact our sales department through the website or by phone.
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