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DL-2-Amino-3-phosphonopropionic acid

CAS 20263-06-3C3H8NO5PBiochemicals & Reagents

DL-2-Amino-3-phosphonopropionic acid (CAS: 20263-06-3, C3H8NO5P) is a chemical compound with a molecular weight of 169.07 g/mol. This phosphonic acid analogue of aspartic acid is recognised for its role in biological systems, particularly as a metabotropic glutamate receptor (mGluR) antagonist. It serves as a valuable tool in neuroscientific research, aiding the study of neuronal signalling pathways and related physiological processes.

IUPAC
3-Phosphono-DL-alanine,AP-3
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DL-2-Amino-3-phosphonopropionic acid (C3H8NO5P) — chemical structure, CAS 20263-06-3; Life Science, fine chemical supplied by Tech Serve Solutions
A-AMBioactive Small MoleculesBiochemicals and ReagentsCell BiologyExcitatory Amino AcidsGPCR ModulatorsGPCR ProteinsModulators and AntibodiesMetabotropic AntagonistsNeuroscience
01 /Applications

Neuroscience Research

Utilised as a selective antagonist for metabotropic glutamate receptors (mGluRs), crucial for investigating neurotransmission and neuronal excitability. Its action helps in understanding the complex roles of glutamate signalling in the central nervous system.

Biochemical Studies

Serves as a key reagent in biochemical assays and studies involving amino acid metabolism and signalling. It aids researchers in dissecting specific biochemical pathways related to excitatory amino acids.

Cell Biology Investigations

Employed in cell-based assays to probe cellular responses influenced by glutamate receptor activity. It is instrumental in understanding cell signalling cascades mediated by GPCRs.

02 /Properties
Molecular weight169.07
Empirical formulaC3H8NO5P
Melting point227-229 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
20263-06-3
MDL number
MFCD00014350
PubChem substance
24277949
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is DL-2-Amino-3-phosphonopropionic acid primarily used for?

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DL-2-Amino-3-phosphonopropionic acid is primarily used in neuroscience research as a metabotropic glutamate receptor (mGluR) antagonist to investigate neurotransmission and neuronal signalling.

What is the CAS number and chemical formula for DL-2-Amino-3-phosphonopropionic acid?

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The CAS number is 20263-06-3, and the chemical formula is C3H8NO5P.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies DL-2-Amino-3-phosphonopropionic acid typically as a research-grade chemical. We do not represent it as USP, BP, EP, or pharmaceutical grade unless explicitly stated in the product specifications.

What are the safety precautions for handling DL-2-Amino-3-phosphonopropionic acid?

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This compound is classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Ensure adequate ventilation, wear appropriate personal protective equipment including eyeshields, gloves, and a dust mask (N95 type recommended), and avoid breathing dust.

How is DL-2-Amino-3-phosphonopropionic acid packed, shipped, and exported?

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DL-2-Amino-3-phosphonopropionic acid is carefully packed according to industry standards to ensure stability during transport. Tech Serve Solutions is experienced in global export and will ensure compliance with all relevant shipping regulations.

How can I request a sample or a quote for DL-2-Amino-3-phosphonopropionic acid?

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To request a sample or a quote, please contact our sales team via the website or direct email, providing your contact details and the quantity required.

Need DL-2-Amino-3-phosphonopropionic acid in a specific grade or volume?