DL-2-Amino-3-phosphonopropionic acid
DL-2-Amino-3-phosphonopropionic acid (CAS: 20263-06-3, C3H8NO5P) is a chemical compound with a molecular weight of 169.07 g/mol. This phosphonic acid analogue of aspartic acid is recognised for its role in biological systems, particularly as a metabotropic glutamate receptor (mGluR) antagonist. It serves as a valuable tool in neuroscientific research, aiding the study of neuronal signalling pathways and related physiological processes.
- IUPAC
- 3-Phosphono-DL-alanine,AP-3

Neuroscience Research
Utilised as a selective antagonist for metabotropic glutamate receptors (mGluRs), crucial for investigating neurotransmission and neuronal excitability. Its action helps in understanding the complex roles of glutamate signalling in the central nervous system.
Biochemical Studies
Serves as a key reagent in biochemical assays and studies involving amino acid metabolism and signalling. It aids researchers in dissecting specific biochemical pathways related to excitatory amino acids.
Cell Biology Investigations
Employed in cell-based assays to probe cellular responses influenced by glutamate receptor activity. It is instrumental in understanding cell signalling cascades mediated by GPCRs.
| Molecular weight | 169.07 |
|---|---|
| Empirical formula | C3H8NO5P |
| Melting point | 227-229 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is DL-2-Amino-3-phosphonopropionic acid primarily used for?
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DL-2-Amino-3-phosphonopropionic acid is primarily used in neuroscience research as a metabotropic glutamate receptor (mGluR) antagonist to investigate neurotransmission and neuronal signalling.
What is the CAS number and chemical formula for DL-2-Amino-3-phosphonopropionic acid?
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The CAS number is 20263-06-3, and the chemical formula is C3H8NO5P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies DL-2-Amino-3-phosphonopropionic acid typically as a research-grade chemical. We do not represent it as USP, BP, EP, or pharmaceutical grade unless explicitly stated in the product specifications.
What are the safety precautions for handling DL-2-Amino-3-phosphonopropionic acid?
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This compound is classified with H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Ensure adequate ventilation, wear appropriate personal protective equipment including eyeshields, gloves, and a dust mask (N95 type recommended), and avoid breathing dust.
How is DL-2-Amino-3-phosphonopropionic acid packed, shipped, and exported?
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DL-2-Amino-3-phosphonopropionic acid is carefully packed according to industry standards to ensure stability during transport. Tech Serve Solutions is experienced in global export and will ensure compliance with all relevant shipping regulations.
How can I request a sample or a quote for DL-2-Amino-3-phosphonopropionic acid?
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To request a sample or a quote, please contact our sales team via the website or direct email, providing your contact details and the quantity required.
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