Diiodosilane
Diiodosilane (CAS: 13760-02-6), with the chemical formula SiH2I2 and a molecular weight of 283.91 g/mol, is a silicon-based compound used as a synthetic reagent. It is particularly noted for its role in reductive iodination processes, notably in the synthesis of the radiopharmaceutical [18F]FDOPA. Its reactivity necessitates careful handling and storage under controlled conditions.
Reagent for Reductive Iodination
Diiodosilane serves as a key reagent in reductive iodination reactions. This application is critical for the synthesis of various complex molecules, including radiotracers used in medical imaging.
Synthesis of [18F]FDOPA
This compound plays a specific role in the synthesis pathway of [18F]FDOPA, a radiopharmaceutical employed in Positron Emission Tomography (PET) for neurological studies and cancer detection.
Chemical Synthesis
As a silicon-based compound, Diiodosilane is utilised in diverse chemical synthesis applications, offering a unique reactivity profile for organic and organometallic chemistry.
| Molecular weight | 283.91 |
|---|---|
| Linear formula | SiH2I2 |
| Boiling point | 56-60 °C/25 mmHg(lit.) |
| Density | 2.834 g/mL at 25 °C(lit.) |
| Storage temperature | 2-8°C |
| Application | Reagent involved in reductive iodination for synthesis of [18F]FDOPA1 |
Hazard statements
- H226Flammable liquid and vapour
- H260In contact with water releases flammable gases
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P223Do not allow contact with water
- P231Handle under inert gas
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P370In case of fire
- P422
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 38 °C / 100.4 °F |
| Transport (UN / ADR) | UN 3129 8(4.3) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-14-20/21/22-34 |
| Safety statements (S) | 16-26-27-28-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diiodosilane used for?
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Diiodosilane is primarily used as a reagent in reductive iodination, notably in the synthesis of [18F]FDOPA.
What is the CAS number and formula for Diiodosilane?
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The CAS number for Diiodosilane is 13760-02-6 and its chemical formula is SiH2I2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diiodosilane as a technical or research grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications. Please refer to the product data sheet for specific purity details.
How should Diiodosilane be handled and stored?
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Diiodosilane is flammable and reacts violently with water, posing significant hazards including severe skin burns and eye damage. It is harmful if swallowed, inhaled, or in contact with skin. Handle with extreme care in a well-ventilated area, using appropriate personal protective equipment such as gloves, goggles, and a full-face respirator. Store under inert gas at 2-8°C, away from moisture and incompatible materials.
How is Diiodosilane packed, shipped, and exported?
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Diiodosilane is carefully packed in UN-approved containers suitable for hazardous and reactive materials. Shipping and export are conducted in compliance with international regulations for dangerous goods, ensuring safe and secure transit.
How can I request a quote or sample for Diiodosilane?
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To request a quote or a sample of Diiodosilane, please contact our sales department through the website or by calling our customer service line, providing your contact details and the product's CAS number.
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