Diethylstilbestrol
Diethylstilbestrol (CAS: 56-53-1), with the molecular formula C18H20O2 and a molecular weight of 268.35 g/mol, is a synthetic non-steroidal estrogen. It is known for its potent estrogenic activity and has been historically used in various medical applications. Due to its significant biological effects and associated risks, its use is now highly regulated and primarily confined to research settings focusing on endocrinology, cancer biology, and drug development.
- IUPAC
- (E)-3,4-Bis(4-hydroxyphenyl)-3-hexene,DES,Stilbestrol
- Synonyms
- (E)-3,4-Bis(4-hydroxyphenyl)-3-hexeneDESStilbestrol
Endocrine Research
Diethylstilbestrol serves as a valuable tool in endocrine research, particularly for studying estrogen receptor interactions and the physiological effects of estrogen modulation. Its synthetic nature allows for controlled experimental designs investigating hormone signaling pathways.
Cancer Biology Studies
As a known carcinogen and endocrine disruptor, Diethylstilbestrol is utilised in cancer research to investigate mechanisms of hormone-dependent cancers and to study the long-term effects of exposure to endocrine-disrupting compounds.
Pharmacological Investigations
This compound is employed in pharmacological studies to understand its mechanism of action, metabolism, and potential therapeutic or adverse effects. Researchers use it to explore drug interactions and the development of anti-cancer therapies targeting hormonal pathways.
| Molecular weight | 268.35 |
|---|---|
| Empirical formula | C18H20O2 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H350May cause cancer
- H360May damage fertility or the unborn child
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P201Obtain special instructions before use
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
- P308IF exposed or concerned
- P501Dispose of contents and container per local regulations
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 45-61-36/37/38-51/53 |
| Safety statements (S) | 53-36/37/39-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ESR1(2099), ESR2(2100), ESRRG(2104)mouse ... Esr1(13982)rat ... Ar(24208), Esr1(24890) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethylstilbestrol used for?
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Diethylstilbestrol (CAS 56-53-1) is primarily used in scientific research for studying endocrine functions, hormone-dependent cancers, and pharmacological mechanisms. Its use is strictly for laboratory research and not for human or animal therapeutic applications.
What are the CAS number and formula for Diethylstilbestrol?
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The CAS number for Diethylstilbestrol is 56-53-1, and its empirical formula is C18H20O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethylstilbestrol as a research-grade chemical. Purity information is available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should Diethylstilbestrol be handled safely?
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Diethylstilbestrol is a potent substance with significant health hazards, including carcinogenicity and reproductive toxicity (H350, H360). Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment such as gloves, eye protection, and a respirator. Avoid exposure and inhalation.
Is Diethylstilbestrol a controlled substance?
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While not explicitly listed as a scheduled controlled substance in all jurisdictions, Diethylstilbestrol is a potent compound with significant health risks and is subject to strict regulatory controls due to its carcinogenic and teratogenic properties. Consult local regulations for specific handling and possession requirements.
How is Diethylstilbestrol packed, shipped, and exported?
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Diethylstilbestrol is carefully packed according to international shipping regulations for hazardous materials. TSS is experienced in exporting chemicals globally, ensuring compliance with all relevant transport and customs requirements.
How can I request a quote or sample for Diethylstilbestrol?
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To request a quote or a sample of Diethylstilbestrol, please contact our sales team through the TSS website or by emailing us directly with your inquiry, including the product CAS number and desired quantity.
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