3-Hydroxy-2-nitropyridine
3-Hydroxy-2-nitropyridine (CAS: 15128-82-2, C5H4N2O3) is a pyridine derivative with a molecular weight of 140.10 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within the realm of heterocyclic chemistry. Its structure lends itself to the creation of novel sulfonates with potential applications in inhibiting cell proliferation and tubulin polymerisation, making it a key intermediate for researchers in medicinal chemistry and drug discovery.
- IUPAC
- 2-Nitro-3-pyridinol
Synthesis of Novel Sulfonates
3-Hydroxy-2-nitropyridine is utilized as a precursor in the synthesis of novel sulfonates. These derivatives have shown potential as potent inhibitors of cell proliferation.
Inhibition of Tubulin Polymerization
The sulfonates derived from 3-Hydroxy-2-nitropyridine have been investigated for their ability to inhibit tubulin polymerization, a critical process in cell division.
Heterocyclic Building Block
As a functionalised pyridine, this compound acts as a versatile building block for constructing more complex heterocyclic systems in organic synthesis.
| Molecular weight | 140.10 |
|---|---|
| Empirical formula | C5H4N2O3 |
| Assay | 97% |
| Application | 3-Hydroxy-2-nitropyridine may be used in the synthesis of novel sulfonates that are potent inhibitors of cell proliferation and tubulin polymerization1. |
| Melting point | 69-71 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Hydroxy-2-nitropyridine used for?
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3-Hydroxy-2-nitropyridine is primarily used as a building block in chemical synthesis, particularly for creating novel sulfonates that act as inhibitors of cell proliferation and tubulin polymerization.
What is the CAS number and chemical formula for 3-Hydroxy-2-nitropyridine?
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The CAS number is 15128-82-2 and the chemical formula is C5H4N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Hydroxy-2-nitropyridine with a minimum purity of 97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 3-Hydroxy-2-nitropyridine be handled safely?
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This compound is a Warning GHS07 substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves, in a well-ventilated area.
How is 3-Hydroxy-2-nitropyridine packed and shipped?
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3-Hydroxy-2-nitropyridine is carefully packed to ensure safe transit and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or obtain a sample of 3-Hydroxy-2-nitropyridine, please contact our sales team through the TSS website or by phone.
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