Diethyl trimethylsilyl phosphite
Diethyl trimethylsilyl phosphite (CAS 13716-45-5) is a chemical compound with the molecular formula (CH3)3SiOP(OC2H5)2 and a molecular weight of 210.28 g/mol. This organophosphorus compound is primarily utilised as a building block and reagent in organic synthesis, particularly in reactions involving phosphorus chemistry. Its properties make it a valuable intermediate for creating more complex molecules in research and development settings.
- IUPAC
- Phosphorous acid diethyl trimethylsilylester
- Synonyms
- Phosphorous acid diethyl trimethylsilylester

Organic Synthesis Reagent
Diethyl trimethylsilyl phosphite serves as a useful reagent in various organic transformations. It can be employed in phosphorylation reactions and as a source of phosphite groups in the synthesis of novel organic compounds.
Building Block for Complex Molecules
This compound acts as a versatile building block in the construction of more elaborate molecular architectures. Its structure allows for incorporation into diverse synthetic pathways within pharmaceutical and materials science research.
Phosphorus Chemistry Intermediate
As a derivative of phosphorous acid, it finds application as an intermediate in specialised phosphorus chemistry. It can participate in reactions leading to phosphorus-containing compounds with potential applications.
| Molecular weight | 210.28 |
|---|---|
| Linear formula | (CH3)3SiOP(OC2H5)2 |
| Assay | ≥95.0% (GC) |
| Boiling point | 58-59 °C/10 mmHg(lit.) |
| Density | 0.921 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.413(lit.)n20/D 1.413 |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 33 °C / 91.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl trimethylsilyl phosphite used for?
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Diethyl trimethylsilyl phosphite (CAS 13716-45-5) is used as a building block and reagent in organic synthesis, particularly in reactions involving phosphorus chemistry.
What is the CAS number and formula for Diethyl trimethylsilyl phosphite?
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The CAS number is 13716-45-5, and the linear formula is (CH3)3SiOP(OC2H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethyl trimethylsilyl phosphite with a purity of ≥95.0% (GC). This product is intended for laboratory and research use, and TSS does not represent it as USP, BP, or EP grade.
How should Diethyl trimethylsilyl phosphite be handled safely?
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Diethyl trimethylsilyl phosphite is a flammable liquid and vapour (H226). Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a suitable respirator, in a well-ventilated area. Store away from ignition sources.
How is Diethyl trimethylsilyl phosphite packed and shipped?
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Diethyl trimethylsilyl phosphite is packed in accordance with safety regulations for flammable liquids and shipped globally by Tech Serve Solutions. Please refer to our shipping policies for detailed information.
How can I request a quote or sample for Diethyl trimethylsilyl phosphite?
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To request a quote or sample for Diethyl trimethylsilyl phosphite, please visit the product page on our website and use the designated contact forms or contact our sales team directly.
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