Diethyl sulfate
Diethyl sulfate (CAS 64-67-5), with the linear formula (C2H5O)2SO2 and a molecular weight of 154.18 g/mol, is a potent ethylating agent. It serves as a crucial reagent in organic synthesis, particularly for introducing ethyl groups onto various substrates. Its utility extends to the preparation of pharmaceuticals, dyes, and other fine chemicals, making it a valuable compound for chemical research and industrial applications.
- IUPAC
- Ethyl sulfate,Sulfuric acid diethyl ester
- Synonyms
- Ethyl sulfateSulfuric acid diethyl ester
Ethylating Agent in Organic Synthesis
Diethyl sulfate is widely employed as an ethylating agent in the synthesis of various organic compounds. It effectively introduces ethyl groups onto nucleophilic sites such as oxygen, nitrogen, and sulfur atoms.
Pharmaceutical Intermediate Production
This compound serves as a key intermediate in the manufacturing processes of numerous pharmaceuticals. Its ability to facilitate specific chemical transformations is vital for constructing complex drug molecules.
Dye and Pigment Manufacturing
In the coloration industry, diethyl sulfate is utilised in the synthesis of certain dyes and pigments. It contributes to the development of chromophores and other structural components required for colour compounds.
Reagent for Chemical Research
As a versatile synthetic reagent, diethyl sulfate is frequently used in academic and industrial research laboratories for exploring new synthetic pathways and developing novel chemical entities.
| Molecular weight | 154.18 |
|---|---|
| Linear formula | (C2H5O)2SO2 |
| Assay | ≥99.0% (GC) |
| Grade | purum |
| Boiling point | 208 °C(lit.) |
| Density | 1.177 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.399(lit.)n20/D 1.400 |
| Melting point | −24 °C(lit.) |
| Vapour pressure | 2 mmHg (55 °C) |
| Vapour density | 5.3 (vs air) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
- H340May cause genetic defects
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 104 °C / 219.2 °F |
| Transport (UN / ADR) | UN 1594 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-46-20/21/22-34 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl Sulfate primarily used for?
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Diethyl sulfate is primarily used as an ethylating agent in organic synthesis for introducing ethyl groups, serving as an intermediate in the production of pharmaceuticals, dyes, and in general chemical research.
What are the CAS number and formula for Diethyl Sulfate?
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The CAS number for Diethyl Sulfate is 64-67-5, and its linear formula is (C2H5O)2SO2.
What grade and purity does Tech Serve Solutions supply for Diethyl Sulfate?
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Tech Serve Solutions supplies Diethyl Sulfate at a minimum assay of ≥99.0% (GC) with a 'purum' grade. We do not represent this product as USP, BP, or EP grade.
What are the main safety concerns when handling Diethyl Sulfate?
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Diethyl sulfate is a dangerous substance, indicated by the GHS05, GHS07, and GHS08 symbols and a 'Danger' signal word. It is harmful if swallowed, inhaled, or in contact with skin, causes severe skin burns and eye damage, and is suspected of causing genetic defects and cancer (H302-H312-H314-H332-H340-H350). Strict adherence to safety protocols, including appropriate personal protective equipment (PPE) such as gloves, goggles, and respiratory protection, is mandatory.
How is Diethyl Sulfate packed, shipped, and exported by TSS?
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Tech Serve Solutions reliably packs, ships, and exports Diethyl Sulfate according to international regulations for hazardous materials. Specific packaging details will be provided upon inquiry.
How can I request a quote or a sample of Diethyl Sulfate?
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To request a quote or a sample of Diethyl Sulfate, please contact our sales team through the website or by phone. We will promptly address your needs.
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