Dichloromethyldiisopropoxyborane
Dichloromethyldiisopropoxyborane (CAS: 62260-99-5; Formula: Cl2CHB[OCH(CH3)2]2) is a specialized organoboron compound. With a molecular weight of 212.91 g/mol, it serves as a valuable reactant in organic synthesis. Its primary applications lie in the formation of carbon-carbon and carbon-heteroatom bonds, and it has been employed in the solid-phase synthesis of aminoboronic acids.
- IUPAC
- (Dichloromethyl)diisopropoxyborane,Diisopropyl (dichloromethyl)boronate,Diisopropyl dichloromethaneboronate
- Synonyms
- (Dichloromethyl)diisopropoxyboraneDiisopropyl (dichloromethyl)boronateDiisopropyl dichloromethaneboronate
![Dichloromethyldiisopropoxyborane (Cl2CHB[OCH(CH3)2]2) — chemical structure, CAS 62260-99-5; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F62260-99-5.png&w=3840&q=75)
Carbon-Carbon Bond Formation
Dichloromethyldiisopropoxyborane acts as a key reactant in synthetic methodologies designed to construct new carbon-carbon bonds, a fundamental process in organic chemistry.
Carbon-Heteroatom Bond Formation
This borane derivative facilitates the creation of bonds between carbon and heteroatoms, expanding its utility in the synthesis of complex organic molecules.
Synthesis of Aminoboronic Acids
It has been utilised in solid-phase synthesis strategies for the preparation of aminoboronic acids, which are significant as inhibitors of the hepatitis C virus NS3 proteinase.
| Molecular weight | 212.91 |
|---|---|
| Linear formula | Cl2CHB[OCH(CH3)2]2 |
| Density | 1.019 g/mL at 25 °C(lit.) |
| Application | Reactant for:• Formation of carbon-carbon and carbon-heteroatom bonds1• Solid phase synthesis of aminoboronic acids as potent inhibitors of the hepatitis C virus NS3 proteinase2 |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 40 °C / 104 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dichloromethyldiisopropoxyborane used for?
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Dichloromethyldiisopropoxyborane is used as a reactant for the formation of carbon-carbon and carbon-heteroatom bonds, and in the solid-phase synthesis of aminoboronic acids.
What are the CAS number and formula for Dichloromethyldiisopropoxyborane?
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The CAS number is 62260-99-5 and the molecular formula is Cl2CHB[OCH(CH3)2]2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dichloromethyldiisopropoxyborane. The specific grade and purity are detailed in the product's specification sheet. It is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Dichloromethyldiisopropoxyborane be handled safely?
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Dichloromethyldiisopropoxyborane is a flammable liquid and vapour (H226) and can cause skin (H315), serious eye (H319), and respiratory irritation (H335). Handle in a well-ventilated area, wear appropriate personal protective equipment including eyeshields and gloves, and keep away from heat and open flames.
Is Dichloromethyldiisopropoxyborane available for export?
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Yes, Tech Serve Solutions, as a specialist global supplier and exporter, can arrange for the export of Dichloromethyldiisopropoxyborane. Please contact us for details on shipping and handling.
How can I request a sample or quote for Dichloromethyldiisopropoxyborane?
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To request a sample or a quote for Dichloromethyldiisopropoxyborane, please use the contact form on our website or reach out to our sales team directly.
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