des-Arg9-[Leu8]-Bradykinin acetate salt
des-Arg9-[Leu8]-Bradykinin acetate salt (CAS: 115035-45-5) is a synthetic peptide analog of bradykinin, with the empirical formula C41H63N11O10 and a molecular weight of 870.01 g/mol. This compound is primarily recognised for its role as a bradykinin-1 receptor (B1R) antagonist. It is frequently employed in biological research to study receptor interactions and cellular signalling pathways, particularly within the fields of cell biology, neuroscience, and peptide research.
- IUPAC
- Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu
![des-Arg9-[Leu8]-Bradykinin acetate salt (C41H63N11O10) — chemical structure, CAS 115035-45-5; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F115035-45-5.png&w=3840&q=75)
Bradykinin Receptor Research
Serves as a B1 receptor antagonist, valuable for investigating the physiological and pharmacological roles of the bradykinin system in various biological contexts. It is often used in comparative studies with B1 receptor agonists.
Cell Signaling Studies
Utilised in cell biology to probe cellular responses mediated by B1 receptors. Its antagonistic properties aid in understanding signal transduction pathways influenced by bradykinin analogs.
Neuroscience Research Tool
Applied in neuroscience to investigate the involvement of bradykinin receptors in neuronal function and signaling, contributing to the understanding of neurological processes.
Peptide Chemistry and Synthesis
As a well-defined peptide, it can serve as a reference standard or a tool in the development and validation of peptide synthesis and analysis techniques.
| Molecular weight | 870.01 |
|---|---|
| Empirical formula | C41H63N11O10 |
| Assay | ≥97% (HPLC) |
| Storage temperature | −20°C |
| Application | The Bradkykinin amid peptide des-Arg9-[Leu8]-Bradykinin is used as a bradykinin-1 receptor (B1R) antagonist frequently in comparison with the B1 receptor agonist des-Arg9-bradykinin. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is des-Arg9-[Leu8]-Bradykinin acetate salt used for?
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des-Arg9-[Leu8]-Bradykinin acetate salt is primarily used as a bradykinin-1 receptor (B1R) antagonist in research settings, particularly within cell biology, cell signaling, neuroscience, and peptide research.
What are the CAS number and molecular formula?
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The CAS number for des-Arg9-[Leu8]-Bradykinin acetate salt is 115035-45-5, and its empirical formula is C41H63N11O10.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies des-Arg9-[Leu8]-Bradykinin acetate salt with an assay of ≥97% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations?
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Handle with care, using appropriate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK rating of 3 in Germany, indicating a high hazard to water.
How is this chemical supplied and exported?
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This chemical is stored at -20°C. Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample?
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Please contact our sales team via the website or designated contact channels to request a quotation or a sample of des-Arg9-[Leu8]-Bradykinin acetate salt.
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