D-Val-Leu-Lys 4-nitroanilide dihydrochloride
D-Val-Leu-Lys 4-nitroanilide dihydrochloride (CAS 62354-43-2), a peptide derivative with the formula C23H38N6O5 · 2HCl and a molecular weight of 551.51 g/mol, serves as a valuable enzyme substrate. It is specifically employed in biochemical research for the assay of proteases, particularly those involved in coagulation pathways and fibrinolysis. Its well-defined structure makes it a reliable tool for studying enzyme kinetics and inhibitor screening in cell biology and neuroscience research.
- IUPAC
- D-Val-Leu-Lys-pNA dihydrochloride,D-Valyl-L-leucyl-L-lysine 4-nitroanilide dihydrochloride
- Synonyms
- D-Valyl-L-leucyl-L-lysine 4-nitroanilide dihydrochloride
Protease Enzyme Substrate
This compound functions as a chromogenic substrate for various proteases, enabling quantitative analysis of enzymatic activity through the release of 4-nitroaniline. It is particularly useful for assays involving enzymes such as plasmin.
Biochemical Research
Used in cell biology and cell signaling studies, D-Val-Leu-Lys 4-nitroanilide dihydrochloride aids in understanding complex biological pathways and enzyme function in biological systems.
Coagulation and Fibrinolysis Studies
Its specificity allows for research into the mechanisms of blood coagulation and fibrinolysis, providing a tool to investigate the activity of related enzymes.
Enzyme Inhibitor Screening
The substrate can be employed in high-throughput screening to identify and characterise novel inhibitors of specific proteases.
| Molecular weight | 551.51 |
|---|---|
| Empirical formula | C23H38N6O5 · 2HCl |
| Storage temperature | −20°C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Val-Leu-Lys 4-nitroanilide dihydrochloride used for?
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D-Val-Leu-Lys 4-nitroanilide dihydrochloride is primarily used as a chromogenic substrate for the assay of protease activity, particularly in research related to coagulation, fibrinolysis, and cell biology.
What are the CAS number and formula for D-Val-Leu-Lys 4-nitroanilide dihydrochloride?
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The CAS number is 62354-43-2 and the formula is C23H38N6O5 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and laboratory use. The specific purity and grade information is available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should D-Val-Leu-Lys 4-nitroanilide dihydrochloride be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is harmful if swallowed, in contact with skin, or if inhaled, and can cause skin, eye, and respiratory irritation.
Is D-Val-Leu-Lys 4-nitroanilide dihydrochloride available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team through the website or by phone, providing the product name and CAS number.
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