D-Sphingosine
D-Sphingosine (CAS: 123-78-4), a synthetic bioactive lipid with the formula C18H37NO2 and a molecular weight of 299.49 g/mol, is a crucial research chemical. It functions as a signaling molecule and enzyme inhibitor. D-Sphingosine is utilised in studies of cell biology, including cell signalling pathways and metabolic processes. Its applications extend to neuroscience research and understanding lipid metabolism.
- IUPAC
- (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol,4-Sphingenine,trans-D-erythro-2-Amino-4-octadecene-1,3-diol
- Synonyms
- (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol4-Sphingeninetrans-D-erythro-2-Amino-4-octadecene-1,3-diol

Cell Biology Research
D-Sphingosine is employed in studies investigating cellular processes, including cell signalling and lipid metabolism. Its role as a bioactive small molecule makes it valuable for understanding complex cellular mechanisms.
Enzyme Inhibition Studies
As a known enzyme inhibitor, D-Sphingosine is used to probe the function of various enzymes. Research has explored its effects on enzymes involved in metabolic pathways and cell signalling cascades.
Neuroscience Research
This compound plays a role in cell signalling within the nervous system. Researchers utilise D-Sphingosine to investigate its impact on neuronal function and related biological pathways.
Metabolomics and Lipid Metabolism
D-Sphingosine is a key lipid involved in various metabolic pathways. It is used in metabolomics research to understand lipid profiles and their implications in biological systems.
| Molecular weight | 299.49 |
|---|---|
| Empirical formula | C18H37NO2 |
| Assay | ~99% (TLC) |
| Solubility | chloroform: complete20 mg/mL, clear, colorless |
| Storage temperature | −20°C |
| Application | The effects of D-Sphingosine, synthetic, on germination activity was studied in the fungus Nomuraea rileyi.8 |
| Biological source | synthetic |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Prkca(24680) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Sphingosine used for?
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D-Sphingosine is used in research for studies in cell biology, cell signalling, neuroscience, enzyme inhibition, and metabolomics. For example, its effects on germination activity in fungi have been studied.
What is the CAS number and formula for D-Sphingosine?
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The CAS number for D-Sphingosine is 123-78-4, and its empirical formula (Hill notation) is C18H37NO2.
What grade and purity does Tech Serve Solutions supply for D-Sphingosine?
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Tech Serve Solutions supplies D-Sphingosine with an assay of ~99% (TLC). This product is intended for research purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
What are the safety precautions for handling D-Sphingosine?
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Handle D-Sphingosine with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The GHS hazard classification indicates a WGK Germany of 3.
How is D-Sphingosine shipped and exported?
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D-Sphingosine is stored at -20°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including D-Sphingosine, adhering to international shipping regulations.
How can I request a quote or sample of D-Sphingosine?
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To request a quote or sample of D-Sphingosine, please contact our sales team through the TSS website, providing your specific requirements.
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