D-Citrulline
D-Citrulline (CAS: 13594-51-9; Formula: C6H13N3O3; Mol. Wt.: 175.19) is an alpha-amino acid with a ureido group. This non-proteinogenic amino acid plays a role in the urea cycle and is a precursor to L-arginine. It is commonly used in chemical biology research, peptide synthesis, and as an unnatural amino acid derivative in chemical synthesis. Tech Serve Solutions supplies D-Citrulline with an assay of ≥99.0%.
- IUPAC
- (R)-2-Amino-5-ureidopentanoic acid

Chemical Biology Research
D-Citrulline serves as a valuable tool in chemical biology for studying amino acid metabolism and the urea cycle. Its specific properties allow researchers to investigate biochemical pathways and enzyme functions.
Peptide Synthesis
As a non-proteinogenic amino acid derivative, D-Citrulline is utilised in the synthesis of modified peptides. This enables the creation of novel peptide structures with tailored properties for various research applications.
Chemical Synthesis
D-Citrulline functions as a building block in organic synthesis. Its unique structure, featuring a ureido group, makes it useful for constructing complex molecules and exploring new synthetic routes.
Biochemical Pathway Studies
Utilised in the investigation of metabolic pathways, particularly the urea cycle, D-Citrulline helps elucidate the biochemical processes involving amino acid transformations and nitrogen excretion.
| Molecular weight | 175.19 |
|---|---|
| Empirical formula | C6H13N3O3 |
| Assay | ≥99.0% |
| Optical activity | [α]20/D −20.5±2.0°, c = 2% in 1 M HCl |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Citrulline used for?
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D-Citrulline is primarily used in chemical biology research, peptide chemistry, and chemical synthesis as an unnatural amino acid derivative. It also plays a role in studying the urea cycle.
What is the CAS number and formula for D-Citrulline?
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The CAS number for D-Citrulline is 13594-51-9, and its empirical formula is C6H13N3O3.
What grade and purity does Tech Serve Solutions supply for D-Citrulline?
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Tech Serve Solutions supplies D-Citrulline with an assay of ≥99.0%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should D-Citrulline be handled and stored?
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Handling D-Citrulline requires appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It should be stored at -20°C.
Is D-Citrulline a controlled substance?
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The provided data does not indicate that D-Citrulline is a controlled substance.
How is D-Citrulline shipped or exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. D-Citrulline is available for export worldwide, adhering to all necessary regulations for chemical shipment.
How can I request a sample or quote for D-Citrulline?
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To request a sample or a quotation for D-Citrulline, please contact our sales team through the website or by phone, providing your specific requirements.
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