Crotonoyl chloride
Crotonoyl chloride (CAS 625-35-4) is an organic compound with the linear formula CH3CH=CHCOCl and a molecular weight of 104.53 g/mol. This acid halide is a reactive intermediate used in organic synthesis. It is a flammable liquid that requires careful handling due to its corrosive nature. Crotonoyl chloride serves as a valuable building block in the chemical industry for the preparation of various organic molecules and specialty chemicals.
Organic Synthesis
Crotonoyl chloride is a versatile reagent used as a precursor in the synthesis of more complex organic molecules. Its acyl chloride functionality readily participates in acylation reactions, forming esters, amides, and other carbonyl derivatives.
Pharmaceutical Intermediates
The compound can be employed in the multi-step synthesis of active pharmaceutical ingredients (APIs) and related compounds. It acts as a key building block for introducing specific structural motifs into target molecules.
Agrochemical Development
Crotonoyl chloride may be used in the development of novel agrochemicals. Its reactivity allows for its incorporation into compounds designed for agricultural applications.
Polymer Chemistry
As a reactive monomer or intermediate, crotonoyl chloride can potentially be utilised in the synthesis of specialised polymers and materials.
| Molecular weight | 104.53 |
|---|---|
| Linear formula | CH3CH=CHCOCl |
| Assay | 90% |
| Boiling point | 120-123 °C(lit.) |
| Density | 1.091 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.459(lit.) |
| Storage temperature | 2-8°C |
| Contains / stabiliser | 1500 ppm hydroquinone as stabilizer |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 35 °C / 95 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34-36/37 |
| Safety statements (S) | 16-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Crotonoyl chloride used for?
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Crotonoyl chloride is primarily used as a reactive intermediate and building block in organic synthesis, including the development of pharmaceuticals and agrochemicals.
What is the CAS number and formula for Crotonoyl chloride?
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The CAS number for Crotonoyl chloride is 625-35-4, and its linear formula is CH3CH=CHCOCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Crotonoyl chloride with an assay of 90%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Crotonoyl chloride be handled safely?
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Crotonoyl chloride is a flammable liquid and causes severe skin burns and eye damage. It may also cause respiratory irritation. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area.
How is Crotonoyl chloride packed, shipped, and exported?
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Crotonoyl chloride is packed and shipped according to international regulations for hazardous materials, including UN 2920, Class 3(8), Packing Group II. Tech Serve Solutions is experienced in global export.
How can I request a sample or quote for Crotonoyl chloride?
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To request a sample or obtain a quote for Crotonoyl chloride, please contact our sales team through the website or by phone.
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