(±)-Coniine
(±)-Coniine (CAS: 3238-60-6), with the molecular formula C8H17N and a molecular weight of 127.23 g/mol, is a neurotoxic alkaloid. It is primarily employed in comparative analyses of alkaloids that interact with nicotinic acid or nicotinic acetylcholine (nAChR) receptors. This compound is also found in plants such as Sambucus nigra (Elderberry).
- IUPAC
- 2-Propylpiperidine
Neuroscience Research
Used as a reference compound in studies investigating the mechanisms of action of alkaloids at nicotinic acetylcholine receptors (nAChRs). Its specific interactions allow for comparative pharmacological analysis.
Phytochemical Analysis
As a known alkaloid from hemlock, it serves as a standard in the identification and quantification of similar compounds in botanical extracts, particularly those derived from plants like Sambucus nigra.
Comparative Pharmacology
Facilitates research comparing the binding affinities and functional effects of various alkaloids on nAChR subtypes, contributing to a deeper understanding of their pharmacological profiles.
| Molecular weight | 127.23 |
|---|---|
| Empirical formula | C8H17N |
| Assay | ≥98% |
| Form | liquid |
| Colour | , clear colorless to yellow-green |
| Density | 0.85 g/mL at 25 °C(lit.) |
| Storage temperature | 2-8°C |
| Application | Coniine, a neurotoxic alkaloid from hemlock, is used in comparative analysis versus other alkaloids that act at the level of the nicotinic acid/nicotinic acetylcholine (nAChR) receptors. |
Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
- H351Suspected of causing cancer
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 48 °C / 118.4 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-40 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-Coniine primarily used for?
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(±)-Coniine is primarily used in comparative analyses of alkaloids that act at the level of nicotinic acid/nicotinic acetylcholine (nAChR) receptors. It is also found in plants like Sambucus nigra.
What are the CAS number and molecular formula for (±)-Coniine?
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The CAS number for (±)-Coniine is 3238-60-6, and its molecular formula is C8H17N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (±)-Coniine with an assay of ≥98%. We do not represent this product as USP, BP, or EP grade.
How is (±)-Coniine supplied and handled?
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(±)-Coniine is a clear, colourless to yellow-green liquid. It is flammable (flash point 48 °C) and toxic by inhalation, skin contact, and ingestion (H331, H311, H301). It is also suspected of causing cancer (H351). Proper personal protective equipment, including eyeshields, gloves, and appropriate respiratory protection, is essential. Storage at 2-8°C is recommended.
Does Tech Serve Solutions export (±)-Coniine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (±)-Coniine.
How can I request a sample or quote for (±)-Coniine?
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Please contact our sales team via the website to request a sample or a quotation for (±)-Coniine.
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