Coenzyme B12
Coenzyme B12 (CAS: 13870-90-1) is an organometallic compound with the formula C72H100CoN18O17P and a molecular weight of 1579.58 g/mol. It functions as a vital cofactor in numerous enzymatic reactions critical for cellular metabolism. This compound plays a key role in biological methylation and isomerisation processes, making it an indispensable tool in biochemical research, cell biology studies, and nutritional investigations.
- IUPAC
- 5′-Deoxyadenosylcobalamine,Adenosyl cobalamine,Cobamamide,DMBC coenzyme
- Synonyms
- 5′-DeoxyadenosylcobalamineAdenosyl cobalamineCobamamideDMBC coenzyme

Biochemical Research
Coenzyme B12 is essential for studying enzymatic pathways involving methyl group transfer and isomerisation. Its role as a cofactor in reactions like methionine synthesis and methylmalonyl-CoA mutase activity is fundamental to understanding metabolic processes.
Cell Biology Studies
Utilised in cell culture and research to investigate cellular energy production and DNA synthesis, as Coenzyme B12 is involved in critical metabolic functions. Its availability can impact cell growth and viability in experimental systems.
Nutrition Research
Serves as a subject of study in nutritional science to understand Vitamin B12's biological significance and metabolic fate. Research often focuses on its absorption, transport, and role in preventing deficiency-related disorders.
Enzyme Inhibition Studies
Can be employed in research to understand enzyme mechanisms and to develop potential enzyme inhibitors. Its interaction with various enzymes provides insights into biochemical regulation.
| Molecular weight | 1579.58 |
|---|---|
| Empirical formula | C72H100CoN18O17P |
| Assay | ≥97.0% |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Coenzyme B12 used for?
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Coenzyme B12 is used in biochemical research, cell biology studies, and nutrition research due to its critical role as a cofactor in enzymatic reactions involving methylation and isomerisation, such as in methionine synthesis and methylmalonyl-CoA mutase activity.
What are the CAS number and formula for Coenzyme B12?
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The CAS number for Coenzyme B12 is 13870-90-1, and its empirical formula is C72H100CoN18O17P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Coenzyme B12 with an assay of ≥97.0%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, pharmacopoeia, nutraceutical, or food grade.
How should Coenzyme B12 be handled and stored?
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Handle Coenzyme B12 with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter (type N95 or P1) may be necessary. Store at -20°C to maintain its stability and integrity.
How is Coenzyme B12 packed, shipped, and exported?
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Coenzyme B12 is carefully packed to ensure stability during transit and is available for export worldwide by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for Coenzyme B12?
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To request a sample or a quote for Coenzyme B12, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
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