Citraconic anhydride
Citraconic anhydride (CAS 616-02-4, C5H4O3) is a cyclic anhydride with a molecular weight of 112.08 g/mol. This compound serves as a valuable building block in organic synthesis and polymer science. Its reactive nature makes it suitable for various polymerisation processes and as an intermediate in the production of fine chemicals. It is also recognised for its applications in protein modification studies.

Polymerisation Monomer
Citraconic anhydride can be utilised as a monomer in the synthesis of polymers. Its incorporation into polymer chains can modify material properties, making it useful in polymer science and materials development.
Organic Synthesis Intermediate
As a reactive cyclic anhydride, it functions as a key intermediate in various organic synthesis pathways. It is employed in the creation of complex molecules and fine chemicals for diverse industrial applications.
Protein Modification Reagent
The compound is used in biochemical research for protein modification, specifically targeting amino acid residues. This application aids in the structural analysis and functional studies of proteins and proteomics.
| Molecular weight | 112.08 |
|---|---|
| Empirical formula | C5H4O3 |
| Assay | ≥99.0% (T) |
| Boiling point | 213-214 °C(lit.) |
| Density | 1.247 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.471(lit.)n20/D 1.472 |
| Vapour density | 4 (vs air) |
| Melting point | 6-10 °C(lit.) |

Hazard statements
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P312Call a POISON CENTER if you feel unwell
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 101 °C / 213.8 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 24-36/37/38 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Citraconic anhydride used for?
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Citraconic anhydride is used as a monomer in polymer science, an intermediate in organic synthesis, and a reagent for protein modification in molecular biology and proteomics.
What is the CAS number and formula for Citraconic anhydride?
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The CAS number for Citraconic anhydride is 616-02-4, and its empirical formula is C5H4O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Citraconic anhydride with an assay of ≥99.0% (T). We do not represent this product as USP, BP, or EP grade.
How should Citraconic anhydride be handled safely?
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Citraconic anhydride is classified as Danger with hazards including toxicity if swallowed, skin irritation, serious eye irritation, and respiratory irritation (H311-H315-H319-H335). Appropriate personal protective equipment, such as gloves, eyeshields, and a suitable respirator, must be used. Handle in a well-ventilated area.
Is Citraconic anhydride a controlled substance?
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The provided data does not indicate that Citraconic anhydride is a controlled substance.
How is Citraconic anhydride packed, shipped, and exported?
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Tech Serve Solutions adheres to all regulations for the safe packing, shipping, and export of chemicals, including hazardous materials like Citraconic anhydride (UN 2810 6.1 / PGIII).
How can I request a sample or quote for Citraconic anhydride?
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To request a sample or quote for Citraconic anhydride, please contact our sales department through the website or by phone.
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