Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride
Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride (CAS: 166023-21-8; Formula: C32H57ClN2O2; MW: 537.26) is a cationic cholesterol derivative. This compound is specifically utilised in molecular biology for efficient gene transfection into mammalian cell lines. It forms liposomes when combined with lipids like L-α-phosphatidylethanolamine, dioleoyl, facilitating the delivery of genetic material.
- IUPAC
- 3β-[N-(Dimethylaminoethane)carbamoyl]cholesterol,DC-Chol
Gene Transfection
Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride is a key component in the formulation of liposomes for efficient gene delivery into mammalian cells. Its cationic nature aids in complexing with nucleic acids.
Liposome Formulation
This derivative is employed in the creation of cationic liposomes when formulated with specific phospholipids, such as dioleoyl phosphatidylethanolamine. These liposomes serve as effective transfection agents.
Molecular Biology Research
Utilised within molecular biology laboratories for applications involving cloning, expression studies, and transformation experiments that require non-viral gene delivery methods.
| Molecular weight | 537.26 |
|---|---|
| Empirical formula | C32H57ClN2O2 |
| Assay | ≥95% |
| Storage temperature | −20°C |
| Application | This cationic cholesterol derivative forms liposomes with L-α-phosphatidylethanolamine, dioleoyl, that efficiently transfect mammalian cell lines. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride used for?
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This cationic cholesterol derivative is primarily used for efficient gene transfection into mammalian cell lines by forming liposomes with phospholipids.
What is the CAS number and formula for Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride?
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The CAS number is 166023-21-8 and the empirical formula is C32H57ClN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥95%. It is suitable for research purposes. TSS does not represent this product as USP, BP, EP or pharmaceutical grade.
How should Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride be handled?
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Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the safety data sheet for full handling instructions.
How is this chemical shipped or exported?
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This product is typically stored at -20°C. TSS is a specialist global supplier and exporter of fine chemicals, ensuring compliant and secure international shipping.
How can I request a sample or quote for Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride?
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Please contact our sales team via the website or directly by phone to request a sample or a quotation for this product.
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