Chloromethyl trifluoromethyl sulfide
Chloromethyl trifluoromethyl sulfide (CAS: 460-58-2) is an organosulfur compound with the formula CF3SCH2Cl and a molecular weight of 150.55 g/mol. This chemical serves as a valuable building block in organic synthesis. It is characterised by its reactive chloromethyl group and the presence of a trifluoromethyl moiety, making it useful for introducing the CF3SCH2- group into various molecular structures. It is supplied by TSS for laboratory and industrial applications.
Organic Synthesis Reagent
Chloromethyl trifluoromethyl sulfide is employed as a reagent in the synthesis of complex organic molecules. Its structure allows for the incorporation of the trifluoromethylthio group, a moiety found in various pharmaceuticals and agrochemicals. The chloromethyl group provides a reactive site for nucleophilic substitution reactions.
Intermediate for Fluorinated Compounds
This compound acts as a key intermediate in the production of specialised fluorinated chemicals. The trifluoromethyl group is highly sought after for its unique electronic properties and metabolic stability, often enhancing the efficacy and pharmacokinetic profiles of active ingredients.
Building Block for Specialty Chemicals
As an organic building block, Chloromethyl trifluoromethyl sulfide is utilised in the development of novel materials and chemical entities. Its bifunctional nature allows for diverse synthetic pathways and the creation of tailored chemical structures for specific industrial needs.
| Molecular weight | 150.55 |
|---|---|
| Linear formula | CF3SCH2Cl |
| Assay | 90% |
| Boiling point | 63.5 °C/740 mmHg(lit.) |
| Density | 1.412 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.3818(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 1 °C / 33.8 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chloromethyl trifluoromethyl sulfide used for?
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Chloromethyl trifluoromethyl sulfide (CAS: 460-58-2) is primarily used as a building block in organic synthesis and as an intermediate for producing specialised fluorinated compounds.
What are the CAS number and chemical formula for Chloromethyl trifluoromethyl sulfide?
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The CAS number is 460-58-2 and the chemical formula is CF3SCH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chloromethyl trifluoromethyl sulfide with an assay of 90%. This product is suitable for research and general chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should Chloromethyl trifluoromethyl sulfide be handled?
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Chloromethyl trifluoromethyl sulfide is classified as Danger, flammable liquid and vapour (H225) and causes severe skin burns and eye damage (H314). Handle with extreme care using appropriate personal protective equipment including faceshields, full-face respirators, gloves, and goggles. Ensure adequate ventilation and follow all safety protocols.
Is Chloromethyl trifluoromethyl sulfide a controlled substance?
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Based on the provided data, there is no indication that Chloromethyl trifluoromethyl sulfide is a controlled substance. However, users should verify local regulations.
How is Chloromethyl trifluoromethyl sulfide packed, shipped, and exported?
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Chloromethyl trifluoromethyl sulfide is shipped under UN 2924, Hazard Class 8(3), Packing Group II. TSS can arrange for global export, adhering to all relevant shipping and customs regulations.
How can I request a sample or quote for Chloromethyl trifluoromethyl sulfide?
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To request a sample or a quotation for Chloromethyl trifluoromethyl sulfide, please contact the Tech Serve Solutions sales team via our website or direct contact details.
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