(+)-Chloromethyl menthyl ether
(+)-Chloromethyl menthyl ether (CAS: 103128-76-3; C11H21ClO) is a chiral ether utilised as a building block in organic synthesis. It is particularly valuable in asymmetric synthesis for the introduction of chiral fragments. With a molecular weight of 204.74 g/mol, this compound offers specific stereochemical control in chemical transformations. Its properties make it suitable for research and development in fine chemical and pharmaceutical intermediate manufacturing.

Chiral Building Block
(+)-Chloromethyl menthyl ether serves as a crucial chiral building block in stereoselective synthesis. It enables the controlled introduction of chirality into target molecules, which is essential for developing enantiomerically pure pharmaceuticals and complex organic compounds.
Asymmetric Synthesis
This compound is employed in asymmetric synthesis methodologies. Its inherent chirality can direct the stereochemical outcome of reactions, facilitating the creation of specific enantiomers with high optical purity, critical for biologically active molecules.
Organic Synthesis
As a versatile reagent in organic synthesis, (+)-Chloromethyl menthyl ether can be used in various transformations. It provides a route to functionalised menthol derivatives and other chiral intermediates for advanced chemical research and development.
| Molecular weight | 204.74 |
|---|---|
| Empirical formula | C11H21ClO |
| Assay | 97% |
| Boiling point | 72 °C/0.4 mmHg(lit.) |
| Density | 0.994 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.467(lit.) |
| Optical activity | [α]24/D +181.0°, c = 2 in methylene chloride |
| Optical purity | ee: 98% (GLC) |
| Storage temperature | −20°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 107 °C / 224.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (+)-Chloromethyl menthyl ether used for?
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(+)-Chloromethyl menthyl ether is primarily used as a chiral building block in asymmetric synthesis and general organic synthesis, allowing for the stereocontrolled introduction of chiral fragments into target molecules.
What are the CAS number and formula for (+)-Chloromethyl menthyl ether?
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The CAS number for (+)-Chloromethyl menthyl ether is 103128-76-3, and its molecular formula is C11H21ClO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (+)-Chloromethyl menthyl ether with a minimum assay of 97%. This product is suitable for research and technical applications; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should (+)-Chloromethyl menthyl ether be handled safely?
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(+)-Chloromethyl menthyl ether is a Warning substance (GHS07) and may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Always handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area.
Is (+)-Chloromethyl menthyl ether a controlled substance?
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The provided data does not indicate that (+)-Chloromethyl menthyl ether is a controlled substance.
How is (+)-Chloromethyl menthyl ether packed and shipped?
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Tech Serve Solutions exports chemicals globally, adhering to all necessary regulations for safe and compliant shipping. Specific packaging details will be provided upon request, tailored to the quantity and destination.
How can I request a sample or quote for (+)-Chloromethyl menthyl ether?
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To request a sample or a quotation for (+)-Chloromethyl menthyl ether, please contact the Tech Serve Solutions sales team via our website or directly by phone. Please specify the desired quantity and delivery location.
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