Chlorodifluoroacetic acid
Chlorodifluoroacetic acid (CAS 76-04-0), with the molecular formula F2ClCCOOH and a molecular weight of 130.48 g/mol, is a halogenated organic acid. It serves as a valuable reagent in organic synthesis. Its corrosive nature requires careful handling. This compound is utilised in various chemical processes and research applications where its unique chemical properties are essential for specific transformations.

Organic Synthesis Reagent
Chlorodifluoroacetic acid acts as a key building block and reagent in the synthesis of complex organic molecules. It is employed in reactions requiring a source of difluoroacetyl groups or in processes where its acidic properties are beneficial.
Chemical Research and Development
This compound is used in laboratory settings for research purposes, exploring novel synthetic pathways and developing new chemical entities. Its reactivity makes it a subject of interest in fluorination chemistry and related fields.
Intermediate in Specialty Chemical Production
It can serve as an intermediate in the production of various specialty chemicals, including pharmaceuticals and agrochemicals, where specific fluorinated moieties are required.
| Molecular weight | 130.48 |
|---|---|
| Linear formula | F2ClCCOOH |
| Assay | 98% |
| Boiling point | 122 °C(lit.) |
| Density | 1.54 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.355(lit.) |
| Melting point | 20-23 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 35 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Chlorodifluoroacetic acid used for?
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Chlorodifluoroacetic acid is primarily used as a reagent in organic synthesis and in chemical research and development. It can also serve as an intermediate in the production of specialty chemicals.
What is the CAS number and formula for Chlorodifluoroacetic acid?
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The CAS number for Chlorodifluoroacetic acid is 76-04-0, and its linear formula is F2ClCCOOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Chlorodifluoroacetic acid with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Chlorodifluoroacetic acid be handled safely?
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Chlorodifluoroacetic acid is a corrosive substance (H314) and requires extreme caution. Handle with appropriate personal protective equipment, including gloves, goggles, and a full-face respirator. Ensure adequate ventilation and avoid contact with skin, eyes, and clothing.
How is Chlorodifluoroacetic acid packed, shipped, and exported?
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Chlorodifluoroacetic acid is packed and shipped in compliance with international regulations for hazardous materials. TSS exports globally, ensuring all shipments meet the necessary transport and customs requirements.
How can I request a quote or sample for Chlorodifluoroacetic acid?
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To request a quote or a sample of Chlorodifluoroacetic acid, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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