Buprenorphine hydrochloride
Buprenorphine hydrochloride (CAS 53152-21-9), with the molecular formula C29H41NO4 · HCl and a molecular weight of 504.10, is a potent opioid agonist and a crucial compound in neuroscientific research. It serves as a valuable tool for studying opioid receptors and their signalling pathways, particularly within the central nervous system. Its applications extend to fundamental research in cell biology and pharmacology, aiding the understanding of complex biological systems.
- IUPAC
- [5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)4,5-epoxy-18,19-dihydo-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol hydrochloride

Neuroscience Research
Buprenorphine hydrochloride is extensively used as a pharmacological tool in neuroscience to investigate the function and regulation of opioid receptors. It aids in understanding pain pathways, addiction mechanisms, and the central nervous system's response to various stimuli.
Cell Signaling Studies
As a modulator of GPCRs, this compound is employed in studies of G protein-coupled receptor signalling pathways. Researchers utilize it to explore cellular responses and downstream effects mediated by opioid receptor activation.
Pharmacological Investigations
It serves as a reference compound in drug discovery and development, allowing for the characterisation of new potential therapeutics targeting the opioid system. Its known pharmacological profile makes it valuable for comparative studies.
| Molecular weight | 504.10 |
|---|---|
| Empirical formula | C29H41NO4 · HCl |


Hazard statements
- H302Harmful if swallowed
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-22-62 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule III; Home Office Schedule 3; psychotrope; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Canada |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Buprenorphine hydrochloride used for?
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Buprenorphine hydrochloride is primarily used in research settings for studying opioid receptors, neuroscience, cell signaling, and as a pharmacological tool in drug discovery.
What is the CAS number and formula for Buprenorphine hydrochloride?
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The CAS number is 53152-21-9, and the formula is C29H41NO4 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Buprenorphine hydrochloride with a minimum assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Buprenorphine hydrochloride be handled?
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Buprenorphine hydrochloride is harmful if swallowed and suspected of damaging fertility or the unborn child. Handle with appropriate personal protective equipment including eyeshields, gloves, and suitable respiratory protection (e.g., N100 respirator cartridges or P3 filter). Ensure adequate ventilation.
Is Buprenorphine hydrochloride a controlled substance?
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Yes, Buprenorphine hydrochloride is a controlled substance, listed under USDEA Schedule III, Home Office Schedule 3, and is considered a psychotrope and controlled drug in Germany. It is regulated under CDSA in Canada but is not available from Canada.
How is Buprenorphine hydrochloride packed and shipped?
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Buprenorphine hydrochloride is carefully packed to maintain stability and integrity during transit. TSS is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote for Buprenorphine hydrochloride?
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Please contact our sales team via the website or email to request a sample or a detailed quotation for Buprenorphine hydrochloride.
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