BrettPhos Pd G3

CAS 1470372-59-8C48H66NO5PPdSCatalysis & Inorganic

BrettPhos Pd G3 (CAS 1470372-59-8) is a third-generation Buchwald palladacycle featuring a biphenyl backbone with phosphine and amine functionalities, complexed with palladium. With a molecular weight of 906.50 g/mol, this organometallic compound is primarily employed as a catalyst in advanced organic synthesis, particularly for cross-coupling reactions. Its specific structure facilitates high efficiency and selectivity in demanding chemical transformations.

IUPAC: BrettPhos-Pd-G3,[(2-Di-cyclohexylphosphino-3,6-dimethoxy-2′,4′,6′- triisopropyl-1,1′-biphenyl)-2-(2′-amino-1,1′ -biphenyl)]palladium(II) methanesulfonate
Synonyms: [(2-Di-cyclohexylphosphino-3,6-dimethoxy-2′,4′,6′- triisopropyl-1,1′-biphenyl)-2-(2′-amino-1,1′ -biphenyl)]palladium(II) methanesulfonate

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BrettPhos Pd G3 (C48H66NO5PPdS) — chemical structure, CAS 1470372-59-8; Chemistry, fine chemical supplied by Tech Serve Solutions

AminesBuilding BlocksC20 to C30+C22 to C40+Chemical SynthesisCross-CouplingEthersNitrogen CompoundsOrganic Building BlocksOxygen Compounds More...

01 /Applications

Catalysis in Cross-Coupling Reactions

BrettPhos Pd G3 serves as a highly effective pre-catalyst for various palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura, Buchwald-Hartwig amination, and Sonogashira couplings. Its advanced ligand structure promotes challenging bond formations with diverse substrates.

Pharmaceutical Intermediate Synthesis

This palladacycle is instrumental in the synthesis of complex organic molecules and pharmaceutical intermediates. Its catalytic activity enables the efficient construction of carbon-carbon and carbon-heteroatom bonds crucial for drug discovery and development.

Fine Chemical Manufacturing

BrettPhos Pd G3 finds application in the manufacturing of fine chemicals where precise control over reaction pathways and high yields are paramount. It is employed in multi-step syntheses requiring robust and reliable catalytic systems.

02 /Properties

Molecular weight	906.50
Empirical formula	C48H66NO5PPdS
Assay	95%
Melting point	150-193 °C (decomposition)

03 /Identifiers & registry

CAS number

1470372-59-8

MDL number

MFCD22572666

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is BrettPhos Pd G3 used for?

BrettPhos Pd G3 is primarily used as a pre-catalyst in palladium-catalyzed cross-coupling reactions for the synthesis of complex organic molecules, pharmaceutical intermediates, and fine chemicals.

What are the CAS number and formula for BrettPhos Pd G3?

The CAS number for BrettPhos Pd G3 is 1470372-59-8. Its empirical formula (Hill notation) is C48H66NO5PPdS, and its molecular weight is 906.50 g/mol.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies BrettPhos Pd G3 with an assay of 95%. This product is intended for research and laboratory use; TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.

How should BrettPhos Pd G3 be handled and stored?

BrettPhos Pd G3 is classified under GHS with a WGK Germany value of 3, indicating it is hazardous to water. It decomposes around 150-193 °C. Handle with appropriate personal protective equipment in a well-ventilated area and store as recommended for air- and moisture-sensitive compounds.

Can Tech Serve Solutions export BrettPhos Pd G3?

Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including BrettPhos Pd G3, to researchers and manufacturers worldwide.