Bosutinib
Bosutinib (CAS 380843-75-4), with the molecular formula C26H29Cl2N5O3, is an off-white to light brown powder. This compound is recognised for its role as a tyrosine kinase inhibitor, primarily investigated for its potential in therapeutic applications, particularly within oncology research. Its specific action targets certain cellular signalling pathways, making it a compound of interest for researchers in cell biology and drug discovery.
- IUPAC
- 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile,SKI-606,WAY-173606
- Synonyms
- 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrileSKI-606WAY-173606
Oncology Research
Bosutinib serves as a valuable tool in cancer research, specifically in studies targeting tyrosine kinases involved in cell proliferation and survival. Its mechanism of action makes it a subject of investigation for potential therapeutic interventions.
Cell Signaling Studies
This compound is utilised in research to explore complex cell signalling pathways, particularly those mediated by non-receptor tyrosine kinases. Understanding these pathways is crucial for developing novel therapeutic strategies.
Drug Discovery and Development
Bosutinib is employed in the early stages of drug discovery as a reference compound or a lead molecule for developing new treatments. Its known inhibitory activity provides a basis for further structural and functional modification.
| Molecular weight | 530.45 |
|---|---|
| Empirical formula | C26H29Cl2N5O3 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | off-white to light brown |
| Solubility | DMSO: ≥15 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H319Causes serious eye irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bosutinib used for?
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Bosutinib is used in scientific research, particularly in oncology and cell signalling studies, as a tyrosine kinase inhibitor. It is investigated for its potential therapeutic applications and in drug discovery.
What is the CAS number and molecular formula for Bosutinib?
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The CAS number for Bosutinib is 380843-75-4, and its molecular formula is C26H29Cl2N5O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bosutinib with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Bosutinib be handled safely?
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Bosutinib is a Warning substance that causes serious eye irritation (H319) and may cause long lasting harmful effects to aquatic life (H413). Wear eye protection (P305 + P351 + P338). In case of contact with eyes, rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Consult a physician if irritation persists.
How is Bosutinib packed and shipped?
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Bosutinib is typically supplied as an off-white to light brown powder and is stored at room temperature. As a global supplier and exporter, Tech Serve Solutions ensures appropriate packaging and shipping procedures are followed.
How can I request a sample or quote for Bosutinib?
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To request a sample or quote for Bosutinib, please contact the Tech Serve Solutions sales team via our website or by phone.
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