Boc-N-Me-D-Leu-OH

CAS 89536-84-5(CH3)2CHCH2CH(COOH)N(CH3)COOC(CH3)3Chemical Synthesis

Boc-N-Me-D-Leu-OH (CAS: 89536-84-5) is a protected N-methyl amino acid derivative with a molecular weight of 245.32 g/mol. It features a tert-butyloxycarbonyl (Boc) protecting group and a methyl group on the nitrogen of D-leucine. This compound is primarily utilised in chemical synthesis and peptide chemistry, particularly for the incorporation of unnatural amino acid residues into peptides and peptidomimetics.

IUPAC: Boc-N-methyl-D-leucine
Synonyms: Boc-N-methyl-D-leucineN-(tert-Butoxycarbonyl)-N-methyl-D-leucine

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Boc-N-Me-D-Leu-OH ((CH3)2CHCH2CH(COOH)N(CH3)COOC(CH3)3) — chemical structure, CAS 89536-84-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisN-Methyl Amino AcidsPeptide Chemistry

01 /Applications

Peptide Synthesis

Utilised as a building block in solid-phase or solution-phase peptide synthesis to introduce N-methylated and unnatural amino acid residues. This modification can influence peptide conformation, stability, and receptor binding.

Chemical Biology Research

Employed in the creation of modified peptides and peptidomimetics for studying biological pathways and protein-ligand interactions. Its unique structure allows for probing structure-activity relationships.

Medicinal Chemistry

Serves as a key intermediate in the synthesis of novel drug candidates and peptidomimetics with enhanced pharmacokinetic properties, such as increased resistance to enzymatic degradation.

Organic Synthesis

Applied as a chiral building block in complex organic synthesis projects requiring the specific stereochemistry and functional groups offered by N-methyl-D-leucine derivatives.

02 /Properties

Molecular weight	245.32
Linear formula	(CH3)2CHCH2CH(COOH)N(CH3)COOC(CH3)3
Assay	≥98.0%

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

89536-84-5

MDL number

MFCD00076953

Beilstein registry

4184551

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-N-Me-D-Leu-OH used for?

Boc-N-Me-D-Leu-OH is used as a protected building block in peptide synthesis, chemical biology research, medicinal chemistry, and general organic synthesis to introduce N-methylated and unnatural amino acid residues.

What is the CAS number and molecular formula for Boc-N-Me-D-Leu-OH?

The CAS number is 89536-84-5. The linear formula is (CH3)2CHCH2CH(COOH)N(CH3)COOC(CH3)3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Boc-N-Me-D-Leu-OH with an assay of ≥98.0%. This product is typically supplied as a research or technical grade chemical. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.

What are the safety considerations when handling Boc-N-Me-D-Leu-OH?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The product is classified under WGK Germany 3, indicating a high hazard level.

How is Boc-N-Me-D-Leu-OH packed, shipped, and exported?

Boc-N-Me-D-Leu-OH is carefully packed in compliance with international shipping regulations to ensure safe transport. Tech Serve Solutions is an experienced global exporter of fine chemicals.