Boc-Lys(Z)-OH
Nε-Z-Nα-Boc-L-lysine (CAS: 2389-45-9; C19H28N2O6) is a protected amino acid crucial for peptide synthesis. With a molecular weight of 380.44 g/mol, this compound features both N-terminal Boc protection and Nε-Z (Cbz) protection on the lysine side chain. It is specifically designed for solid-phase peptide synthesis (SPPS) applications, enabling the controlled incorporation of lysine residues with protected side chains into growing peptide chains.
- IUPAC
- Nα-Boc-Nε-Cbz-L-lysine,Nα-Boc-Nε-Z-L-lysine,Nε-Z-Nα-Boc-L-lysine
- Synonyms
- Nα-Boc-Nε-Cbz-L-lysineNα-Boc-Nε-Z-L-lysineNε-Z-Nα-Boc-L-lysine

Solid-Phase Peptide Synthesis (SPPS)
Nε-Z-Nα-Boc-L-lysine serves as a key building block in SPPS. Its dual protection strategy allows for sequential amino acid coupling, with the Nε-Z group protecting the lysine side chain during peptide chain elongation.
Peptide Research and Development
This protected amino acid is utilised in the synthesis of complex peptides for research purposes, including therapeutic peptide development and biochemical studies where precise side-chain modification is required.
Biochemical Reagent
As a modified amino acid, it is valuable for researchers in biochemistry and molecular biology investigating protein structure, function, and modifications.
| Molecular weight | 380.44 |
|---|---|
| Empirical formula | C19H28N2O6 |
| Storage temperature | −20°C |
| Application | Nε-Z-Nα-Boc-L-lysine is an N-terminal protected amino acid used in solid-phase peptide synthesis (SPPS) to make peptides containing Nepsilon protected lysyl side chains. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nε-Z-Nα-Boc-L-lysine used for?
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Nε-Z-Nα-Boc-L-lysine is used as a protected amino acid in solid-phase peptide synthesis (SPPS) to incorporate lysine residues with protected side chains into peptides.
What are the CAS number and molecular formula of Nε-Z-Nα-Boc-L-lysine?
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The CAS number is 2389-45-9 and the molecular formula is C19H28N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nε-Z-Nα-Boc-L-lysine primarily for research and laboratory use. The specific assay and purity are detailed in the product specifications; it is not supplied as USP, BP, or EP grade.
How should Nε-Z-Nα-Boc-L-lysine be handled?
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Handle Nε-Z-Nα-Boc-L-lysine with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter (type N95 or P1) is recommended when handling. The compound has a WGK Germany classification of 3, indicating a significant hazard to water.
How is Nε-Z-Nα-Boc-L-lysine packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports Nε-Z-Nα-Boc-L-lysine according to international regulations for chemical transport, ensuring secure and compliant delivery globally.
How can I request a sample or quote for Nε-Z-Nα-Boc-L-lysine?
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To request a sample or quote for Nε-Z-Nα-Boc-L-lysine, please contact our sales department through the website or by phone, providing your specific requirements.
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