Boc-D-His(Bom)-OH
Nα-Boc-π-Bom-D-histidine (CAS: 99310-01-7) is a protected derivative of D-histidine, featuring tert-butyloxycarbonyl (Boc) protection on the alpha-amino group and a benzyloxymethyl (Bom) group on the imidazole ring. This compound is essential in peptide synthesis, particularly for creating peptides with specific D-histidine residues. Its protected nature allows for controlled coupling reactions in complex molecular assembly.
- IUPAC
- Nα-Boc-π-Bom-D-histidine,Nα-Boc-N(im)-benzyloxymethyl-D-histidine
- Synonyms
- Nα-Boc-π-Bom-D-histidineNα-Boc-N(im)-benzyloxymethyl-D-histidine
Peptide Synthesis
Used as a building block in solid-phase or solution-phase peptide synthesis to incorporate protected D-histidine residues. The orthogonal protecting groups (Boc and Bom) allow for selective deprotection strategies during chain elongation.
Chemical Biology Research
Enables the synthesis of modified peptides and peptidomimetics for studying biological pathways, protein-ligand interactions, and enzyme mechanisms where histidine plays a critical role.
Drug Discovery and Development
Facilitates the creation of novel peptide-based therapeutics or diagnostic agents. The specific stereochemistry (D-form) and protected side chain are valuable for designing molecules with altered stability or receptor binding properties.
Organic Synthesis
Serves as a versatile chiral intermediate in complex organic synthesis projects requiring a protected D-histidine moiety for further chemical transformations.
| Molecular weight | 375.42 |
|---|---|
| Empirical formula | C19H25N3O5 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-His(Bom)-OH used for?
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Boc-D-His(Bom)-OH is primarily used as a protected amino acid building block in peptide synthesis and chemical biology research, enabling the controlled incorporation of D-histidine residues into peptides and complex molecules.
What is the CAS number and formula for Boc-D-His(Bom)-OH?
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The CAS number for Boc-D-His(Bom)-OH is 99310-01-7, and its empirical formula is C19H25N3O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-D-His(Bom)-OH with an assay of ≥98.0% determined by TLC. We do not represent this product as USP, BP, EP, or for use in pharmaceutical, food, or nutraceutical applications.
What are the safety and handling considerations for Boc-D-His(Bom)-OH?
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Boc-D-His(Bom)-OH is classified under WGK 3 in Germany. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter, should be used during handling to prevent exposure.
Is Boc-D-His(Bom)-OH a controlled substance?
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The provided data does not indicate that Boc-D-His(Bom)-OH is a controlled substance.
How is Boc-D-His(Bom)-OH packaged and shipped?
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Tech Serve Solutions exports fine chemicals globally. Packaging and shipping details are provided upon request, adhering to all relevant regulations for chemical transport.
How can I request a quote or sample for Boc-D-His(Bom)-OH?
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To request a quote or sample for Boc-D-His(Bom)-OH, please contact our sales team through the website or by phone, providing your specific requirements.
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