Boc-Aib-OH
Boc-Aib-OH (CAS: 30992-29-1) is an unnatural amino acid derivative with a molecular weight of 203.24 g/mol. This compound, chemically known as α-(Boc-amino)isobutyric acid, is a valuable building block in peptide synthesis and chemical biology research. Its structure facilitates the incorporation of non-proteinogenic amino acids into peptide chains, offering unique structural and functional properties.
- IUPAC
- α-(Boc-amino)isobutyric acid,Boc-α-methylalanine
- Synonyms
- α-(Boc-amino)isobutyric acidBoc-α-methylalanine

Peptide Synthesis
Boc-Aib-OH serves as a protected unnatural amino acid for incorporation into synthetic peptides. It is particularly useful for introducing α,α-disubstituted amino acid residues, which can enhance peptide stability and conformational rigidity.
Chemical Biology Research
Researchers utilise Boc-Aib-OH to explore the structure-activity relationships of peptides and proteins. The inclusion of Aib residues can modulate biological activity and membrane permeability.
Chemical Synthesis
As a versatile building block, Boc-Aib-OH is employed in various organic synthesis pathways, particularly those requiring the introduction of protected α-aminoisobutyric acid moieties.
| Molecular weight | 203.24 |
|---|---|
| Linear formula | (CH3)3CO2CNHC(CH3)2CO2H |
| Assay | ≥99.0% (T) |
| Melting point | 118-122 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Aib-OH used for?
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Boc-Aib-OH is primarily used as a building block in peptide synthesis and for research in chemical biology and organic synthesis, enabling the incorporation of unnatural amino acid residues.
What are the CAS number and formula for Boc-Aib-OH?
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The CAS number for Boc-Aib-OH is 30992-29-1. Its linear formula is (CH3)3CO2CNHC(CH3)2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Aib-OH with an assay of ≥99.0% (T). This is a technical/research grade product, and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for Boc-Aib-OH?
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Appropriate personal protective equipment, including eyeshields and gloves, should be used when handling Boc-Aib-OH. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3.
How is Boc-Aib-OH packed, shipped, and exported?
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Boc-Aib-OH is carefully packaged to ensure stability during transit and is available for global export. Specific packaging details can be provided upon request.
How can I request a sample or quote for Boc-Aib-OH?
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To request a sample or a quote for Boc-Aib-OH, please contact our sales team through the website or by phone, providing your specific requirements.
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