Boc-β-(2-thienyl)-D-Ala-OH
Boc-β-(2-thienyl)-D-Ala-OH (CAS: 78452-55-8), with the molecular formula C12H17NO4S and a molecular weight of 271.33 g/mol, is a protected unnatural amino acid derivative. It serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology. This compound is utilised for the introduction of a thienylalanine residue into peptide chains or other complex molecules, enabling the study of modified protein structures and functions.
- IUPAC
- (R)-2-(Boc-amino)-3-(2-thienyl)propionic acid,Boc-3-(2-thienyl)-D-alanine
Peptide Synthesis
This N-protected unnatural amino acid is employed in solid-phase or solution-phase peptide synthesis to incorporate a 2-thienylalanine moiety. This allows for the creation of modified peptides with altered conformational properties or biological activities.
Chemical Biology Research
Boc-β-(2-thienyl)-D-Ala-OH is used as a tool in chemical biology to investigate the impact of unnatural amino acids on protein structure, function, and interactions. It can be incorporated into peptides or proteins to probe specific biological processes.
Medicinal Chemistry
The compound serves as an intermediate in the synthesis of novel drug candidates. The thienyl group can mimic phenyl rings or introduce specific electronic and steric properties beneficial for molecular design in medicinal chemistry.
Organic Synthesis
As a chiral building block, it is utilised in complex organic synthesis pathways where the specific stereochemistry and functional groups are required for constructing target molecules.
| Molecular weight | 271.33 |
|---|---|
| Empirical formula | C12H17NO4S |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-β-(2-thienyl)-D-Ala-OH used for?
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Boc-β-(2-thienyl)-D-Ala-OH is primarily used as a protected unnatural amino acid in peptide synthesis, chemical biology research, medicinal chemistry, and general organic synthesis for constructing molecules with specific structural and functional characteristics.
What are the CAS number and formula for this compound?
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The CAS number is 78452-55-8, and the empirical formula is C12H17NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-β-(2-thienyl)-D-Ala-OH with a purity of ≥98.0% (HPLC). This is a research-grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for Boc-β-(2-thienyl)-D-Ala-OH?
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Handling this compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if respiratory protection is needed. It is classified under WGK Germany 3, indicating a high hazard to water.
How is Boc-β-(2-thienyl)-D-Ala-OH packed, shipped, and exported?
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TSS professionally packs, ships, and exports fine chemicals globally, ensuring compliance with all relevant regulations for safe transport.
How can I request a sample or quote for Boc-β-(2-thienyl)-D-Ala-OH?
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To request a sample or a quote, please contact the TSS sales team through our website or by phone.
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