Biphenyl-4-carbonyl chloride
Biphenyl-4-carbonyl chloride (CAS: 14002-51-8) is an organic compound with the linear formula C6H5C6H4COCl and a molecular weight of 216.66 g/mol. As an acid halide and a carbonyl compound, it serves as a valuable building block in organic synthesis. Its reactivity makes it suitable for introducing the biphenyl-4-carbonyl moiety into various molecules, facilitating the creation of complex organic structures.
- IUPAC
- 4-Phenylbenzoyl chloride
- Synonyms
- 4-Phenylbenzoyl chloride

Organic Synthesis Intermediate
Biphenyl-4-carbonyl chloride is a key intermediate in the synthesis of more complex organic molecules. It is utilised in acylation reactions to introduce the biphenyl-4-carbonyl group into diverse chemical structures.
Pharmaceutical Building Block
This compound acts as a fundamental building block in the development of novel pharmaceutical agents. Its structure can be incorporated into drug candidates, contributing to their overall chemical profile and potential therapeutic activity.
Material Science Research
Biphenyl-4-carbonyl chloride finds application in material science for the synthesis of specialised polymers and organic materials. The biphenyl moiety can impart desirable properties such as thermal stability and rigidity to resulting materials.
| Molecular weight | 216.66 |
|---|---|
| Linear formula | C6H5C6H4COCl |
| Assay | 97% |
| Melting point | 110-112 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3261 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Biphenyl-4-carbonyl chloride used for?
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Biphenyl-4-carbonyl chloride is primarily used as an intermediate and building block in organic synthesis, particularly for introducing the biphenyl-4-carbonyl group into pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and formula for Biphenyl-4-carbonyl chloride?
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The CAS number is 14002-51-8 and the linear formula is C6H5C6H4COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Biphenyl-4-carbonyl chloride with an assay of 97%. This product is intended for research and technical purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Biphenyl-4-carbonyl chloride be handled?
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Biphenyl-4-carbonyl chloride is classified as corrosive (H314 - Causes severe skin burns and eye damage). Handle with extreme caution, wearing appropriate personal protective equipment including gloves, eye protection, and protective clothing. Ensure adequate ventilation.
How is Biphenyl-4-carbonyl chloride packed and shipped?
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This chemical is packed in accordance with UN 3261, Hazard Class 8, Packing Group II regulations for transportation. Tech Serve Solutions exports fine chemicals globally.
How can I request a quote or sample?
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To request a quote or a sample of Biphenyl-4-carbonyl chloride, please contact the Tech Serve Solutions sales team via our website or direct inquiry.
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