Bicine
Bicine (CAS 150-25-4, C6H13NO4, MW: 163.17) is a synthetic biological buffer, commonly utilised in biochemical research, particularly for low-temperature applications. Its properties make it suitable for preparing stable substrate solutions and as a spacer in protein fractionation techniques like isotachophoresis. Bicine is supplied by Tech Serve Solutions as a high-quality powder, ideal for laboratory and research settings.
- IUPAC
- N,N-Bis(2-hydroxyethyl)glycine
Low-Temperature Biochemical Work
Bicine is recommended as a buffer for biochemical experiments conducted at reduced temperatures due to its stable buffering capacity within its useful pH range.
Serum Guanase Determination
It is employed in the preparation of stable substrate solutions essential for the accurate determination of serum guanase levels.
Plasma Protein Fractionation
Bicine acts as a spacer in the fractionation of plasma proteins using techniques such as isotachophoresis with Sephadex®.
| Molecular weight | 163.17 |
|---|---|
| Empirical formula | C6H13NO4 |
| Form | powder |
| Density | 1.05 g/mL at 20 °C |
| pH | 5.0±0.2 |
| Concentration | 1 M in H2O |
| Storage temperature | 2-8°C |
| Impurities tested | DNases, none detectedRNases, none detectedphosphatases, none detectedproteases, none detected |
| Application | Recommended buffer for low temperature biochemical work.1 Used in the preparation of stable substrate solution for serum guanase determination.2 Spacer in plasma protein fractionation with Sephadex® by isotachophoresis.3 |
| Suitability | in accordance for filter test |
| Biological source | from synthetic |
| Quality Level | ELITE |
|---|---|
| Product Line | PharmaGrade |
| Pka 25 °C | 8.3 |
| Foreign Activity | Cytotoxicity, DNase, NICKase, RNase, and Protease; tested |
| Uv Absorption | λ: 260 nm Amax: λ: 280 nm Amax: <0.04 |
| Useful Ph Range | 7.6 - 9.0 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bicine used for?
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Bicine is used as a buffer in biochemical research, particularly for low-temperature applications, in the preparation of stable substrate solutions for serum guanase determination, and as a spacer in plasma protein fractionation.
What is the CAS number and formula for Bicine?
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The CAS number for Bicine is 150-25-4, and its empirical formula is C6H13NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bicine as an ELITE grade, suitable for advanced research and pharmaceutical applications. It is tested for cytotoxicity, DNase, NICKase, RNase, and Protease activity, with no detected DNases, RNases, phosphatases, or proteases.
What are the safety and handling recommendations for Bicine?
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Bicine has a WGK Germany rating of 3, indicating it is hazardous for water. Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling and disposal information.
How is Bicine packed, shipped, and exported?
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Bicine is supplied as a powder and stored at 2-8°C. Tech Serve Solutions specialises in global export of fine chemicals, ensuring compliance with international shipping regulations for chemical products.
How can I request a sample or quote for Bicine?
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To request a sample or a quote for Bicine, please contact our sales team through the TSS website, providing your specific requirements and shipping details.
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