Benzofuran-2-carbonyl chloride
Benzofuran-2-carbonyl chloride (CAS: 41717-28-6; Formula: C9H5ClO2) is a valuable heterocyclic building block with a molecular weight of 180.59 g/mol. This compound serves as a key intermediate in organic synthesis, facilitating the introduction of the benzofuran-2-carbonyl moiety into various molecular structures. It is primarily utilised in the research and development of novel chemical entities, particularly within pharmaceutical and materials science research.

Organic Synthesis Intermediate
Benzofuran-2-carbonyl chloride acts as a versatile intermediate for the synthesis of more complex organic molecules. Its reactive acyl chloride group readily participates in acylation reactions with nucleophiles such as alcohols, amines, and thiols.
Pharmaceutical Research
This compound is employed in the development of new pharmaceutical agents. The benzofuran scaffold is present in various biologically active compounds, and this derivative allows for targeted modifications and structure-activity relationship studies.
Materials Science
Benzofuran derivatives can be incorporated into polymers and other advanced materials. Benzofuran-2-carbonyl chloride can be used to functionalise materials or as a monomer component in specific polymerisation processes.
| Molecular weight | 180.59 |
|---|---|
| Empirical formula | C9H5ClO2 |
| Assay | 97% |
| Melting point | 53-57 °C |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Transport (UN / ADR) | UN 3261 8 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Benzofuran-2-carbonyl chloride primarily used for?
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Benzofuran-2-carbonyl chloride is primarily used as an intermediate in organic synthesis, particularly in pharmaceutical research and materials science, to introduce the benzofuran-2-carbonyl group into target molecules.
What are the CAS number and molecular formula for Benzofuran-2-carbonyl chloride?
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The CAS number for Benzofuran-2-carbonyl chloride is 41717-28-6, and its molecular formula is C9H5ClO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Benzofuran-2-carbonyl chloride with a minimum assay of 97%. This product is suitable for research and general chemical synthesis and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Benzofuran-2-carbonyl chloride be handled safely?
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Benzofuran-2-carbonyl chloride is a Warning irritant (H319). Handle with appropriate personal protective equipment, including eye protection and gloves, in a well-ventilated area. In case of eye contact, rinse cautiously with water for several minutes and seek medical advice. Avoid dust formation and inhalation.
Is Benzofuran-2-carbonyl chloride shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Benzofuran-2-carbonyl chloride, which can be shipped internationally.
How can I request a sample or quote for Benzofuran-2-carbonyl chloride?
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To request a sample or a quote for Benzofuran-2-carbonyl chloride, please contact our sales team through the website or by phone, providing your specific requirements.
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