ARP 101
ARP 101 (CAS: 849773-64-4) is a selective inhibitor of MMP-2 with the molecular formula C20H26N2O5S and a molecular weight of 406.50 g/mol. This compound plays a role in diverse physiological processes, including wound healing, cancer metastasis, and tissue remodelling. It is primarily utilized in biochemical research for studying matrix metalloproteinase activity and related biological pathways.
- IUPAC
- (2R)-2-[([1,1′-Biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-3-methyl-butanamide,(R)-N-Hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide
Matrix Metalloproteinase Inhibition
ARP 101 functions as a selective inhibitor for MMP-2, a key enzyme involved in extracellular matrix degradation. This makes it a valuable tool for researchers studying the role of MMPs in physiological and pathological processes.
Cancer Research
Given its ability to inhibit MMP-2, which is implicated in cancer metastasis and angiogenesis, ARP 101 is used in research settings to investigate mechanisms of tumour progression and potential therapeutic strategies.
Tissue Remodelling Studies
The compound's involvement in physiological processes like wound healing and tissue remodelling makes it relevant for research into these areas. It aids in understanding the enzymatic regulation of extracellular matrix dynamics.
| Molecular weight | 406.50 |
|---|---|
| Empirical formula | C20H26N2O5S |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Solubility | DMSO: >20 mg/mLH2O: insoluble |
| Storage temperature | −20°C |
| Application | ARP 101 is a MMP-2 selective inhibitor. ARP 101 has diverse physiological roles including wound healing, cancer metastasis, angiogenesis, tissue remodeling in development, and embryogenesis. |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is ARP 101 used for?
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ARP 101 is primarily used in biochemical research as a selective inhibitor of MMP-2. It is employed to study its diverse physiological roles, including wound healing, cancer metastasis, angiogenesis, and tissue remodelling.
What are the CAS number and formula for ARP 101?
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The CAS number for ARP 101 is 849773-64-4, and its molecular formula is C20H26N2O5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies ARP 101 with an assay of ≥98% (HPLC). This is a research-grade chemical and is not represented as USP, BP, or EP grade.
How should ARP 101 be handled safely?
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ARP 101 is classified with GHS06 symbol and a Danger signal word, indicated by hazard statement H301 (Toxic if swallowed). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, must be used. Handle with extreme caution.
How is ARP 101 typically supplied and exported?
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ARP 101 is supplied as a solid and stored at -20°C. As a specialist supplier, Tech Serve Solutions exports fine chemicals globally, adhering to all necessary regulations for safe transport.
How can I request a quote or sample for ARP 101?
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To request a quote or sample for ARP 101, please contact our sales team through the website or by phone. Provide your contact details and the quantity required.
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